The human chromokinesin Kid/kinesin-10, a plus end-directed microtubule (MT)-based motor with both microtubule- and DNA-binding domains, is required for proper chromosome alignment at the metaphase plate. Here, we performed RNA interference experiments to deplete endogenous Kid from HeLa cells and confirmed defects in metaphase chromosome arm alignment in Kid-depleted cells. In addition, we not...

The use of computers is increasing in mathematics education. This trend is supported by the NCTM standards and computational power applicable in mathematical curricula. As part of CAI software, Linear Kid was designed, developed and evaluated reflecting upon NCTM standards. Linear Kid is a computer-based peer tutoring system where students become active learners who are guided to learn by teach...

Is overall performance of an AI-based embryo evaluation model improved by including discarded embryos during training compared to using only transferred with known implantation data (KID)? A set 14,643 KID fetal heart (4,337 FH+ and 10,307 FH-) incubated for at least 4 days was obtained from 18 different clinics. The also included 23,674 either cryopreserved or unknown FH 101,153 that were thus...

Growth data were collected over 4 yr from 349 Brahman-Hereford F1, first-calf, lactating females that had been allotted as weanlings to either semiarid extensive rangeland (Uvalde) or humid improved Bermudagrass pasture (Overton) and to one of four herbage allowance levels at each location as yearlings. Heifers were wintered according to systems in local practice and maintained on allotted fora...

We report the case of a 17-year-old girl with keratitis, ichthyosis, and deafness (KID) syndrome. As a complication of her KID syndrome she developed squamous cell carcinoma at the left index finger. Additional clinical features were multiple soft tissue lesions over the scalp mimicking metastatic disease on 18F-FDG PET/CT. To our knowledge, this is the first case report about the uptake patter...

background: allogeneic hematopoietic stem cell transplantation (hsct) is a curative treatment option for many patients with acute myeloid leukemia (aml); however, it can lead to complications of graft-versus-host-disease (gvhd) which can affect the quality of life and overall survival. the aim of this study was to assess the effects of both acute and chronic gvhd on survival rate in patients wi...

background: esophageal cancer is often diagnosed in the last stages where the chance of patient’s survival is very low. the aim of this systematic review was presentation of valid estimation of survival in patients with esophageal cancer in different regions of iran. methods: a systematic review was carried out based on the reliable domestic medical databases including: sid, magiran, irandoc an...

this study was conducted to evaluate the effects of beta plus probiotic, a mixture of bacillius leicheniformic and bacillius subtilis , on the growth performance and intestinal microbial flora of caspian trout ( salmo caspius ). a basal diet was formulated and supplemented with beta plus at 0, 0.5 and 1 g kg -1 , leading to three experimental diets. each experimental diet was randomly assigned ...