introduction: the prevalence of hypertension in patients with type 2 diabetes (t2d) is approximately twice as much as healthy people. this study was designed to determine the effect of l-arginine supplementation on blood pressure in patients with t2d. methods: in a double-blind randomized clinical trial, 75 t2d were randomly divided into three groups (3 g/d and 6 g/d of l-arginine and placebo) ...

introduction: the mechanisms of hepatic encephalopathy are not fully understood. moreover, there is no comprehensive data concerning the effects of nitric oxide (no) system on anxiolytic-like behaviors induced by bile duct ligation (bdl). methods: male mice weighing 25-30 g were used and anxiety-like behaviors were tested using hole-board task. results: the data indicated that cholestasis incre...

introduction: this study was conducted to determine the possible beneficial results of l-arginine on prefrontal cortex of rats which impressed by immobilization stress to define the synchronous impression of stress and nitric oxide (no) on evolution of prefrontal cortex of rats after birth. methods: forty-eight one month, male wistar rats were divided into two groups: stressed and non-stressed....

We use the magnetic field distribution of an azimuthally polarized focused laser beam to excite a magnetic dipole transition in Eu^{3+} ions embedded in a Y2O3 nanoparticle. The absence of the electric field at the focus of an azimuthally polarized beam allows us to unambiguously demonstrate that the nanoparticle is excited by the magnetic dipole transition near 527.5 nm. When the laser wavelen...

  The involvement of nitric oxide (NO) in the reinforcing properties of opiate reward was studied by examining the effect of a NO precursor (L-arginine) and a NO synthase inhibitor (L-NAME) on the rate of intravenous self-administration of morphine. This experiment was investigated in male albino Sprague Dawley rats (300 ± 50 g). At doses of 5 and 10 mg/kg (i.p.), L-arginine decreased morphine ...

OBJECTIVES The objective of this study was to identify an injection strategy leading to repeatable nanoparticle deposition patterns in tumours and to quantify volumetric heat generation rate distribution based on micro-CT Hounsfield unit (HU) in magnetic nanoparticle hyperthermia. METHODS In vivo animal experiments were performed on graft prostatic cancer (PC3) tumours in immunodeficient mice...