Although increased circulating tumor antigen-specific CD8(+) T cells can be achieved by vaccination or adoptive transfer, tumor progression nonetheless often occurs through resistance to effector function. To develop a model for identifying mechanisms of resistance to antigen-specific CTLs, poorly immunogenic B16-F10 melanoma was transduced to express the K(b)-binding peptide SIYRYYGL as a gree...

We present a data-driven approach which exploits word alignment in a large parallel corpus with the objective of identifying those verband adjective-preposition combinations which are difficult for L2 language learners. This allows us, on the one hand, to provide language-specific ranked lists in order to help learners to focus on particularly challenging combinations given their native languag...

There are obvious issues with regard to teaching pronunciation to Gujarati Speakers of English (GSE). These issues have its root in the inherent difference between the phonology of Gujarati and English at both segmental and supra-segmental level. There is sufficient research evidence to prove that these phonological differences are largely responsible for problems in teaching English pronunciat...

The problems encountered by English learners whose mother tongue does not have an article system have been researched extensively. The problems encountered by learners whose mother tongue does have an article system, such as Arabic, have been studied less. This article describes an enquiry into article system errors in a corpus of English writing by tertiary-level L1 Arabic speakers. Frequencie...

A bidentate iridium carbene complex, Ir(κC,O-L1)(COD), has been synthesised which contains a strongly electron donating carbene ligand that is functionalised by a cis-spanning phenolate group. This complex acts as a precursor to effective magnetisation transfer catalysts which form after reaction with H2 and a suitable two electron donor. In solvents such as benzene, containing pyridine, they a...

The acquisition of argument structures has been studied by a variety of second language acquisition scholars within the past two decades (Atay, 2010; Can, 2009; Chay, 2006, & Kras, 2007, among others). In the present study, ‘Predicate’ as the most substantial element of a sentence is investigated. There are three English verb-types which seem to be more problematic for Persian EFL learners: (a)...

Adult second language (L2) learners are faced with a particular challenge relative to child L2 learners—adults arrive at the language learning situation with a fully-formed and ingrained first language (L1) system in place. As a result, adult learners are particularly influenced by the transfer of information from L1 to L2 (e.g., MacWhinney, 2005). Although transfer assists learning in some dom...

This study investigated the effect of treatment in the second language (L2) for a previously proficient French-English bilingual with aphasia, at 5 years post-stroke. Assessment on the Bilingual Aphasia Test (BAT) enabled objective measurement of language skills in each language, and comparison across languages, before and after treatment in L2 (English). Previous therapy had been provided excl...