نتایج جستجو برای: ld50

تعداد نتایج: 2605  

Journal: :journal of agricultural science and technology 2010
a. a. pourmirza

the population response of heliothis armigera larvae to nuclear polyhedrosis virus (npv) was investigated. the virus was introduced by permitting the larvae to feed on lettuce leaves. median lethal doses (ld50) were determined. the estimated ld50 values for the first, second, third, early, and late fourth larval instars were 5, 141, 1226, 5168 and 24553 polyhedra per larva respectively. in ...

2014
Sanaa K Bardaweel Khaled A Tawaha Mohammad M Hudaib

BACKGROUND Anthemis palestina (Asteraceae) extends across the Mediterranean region, southwest Asia and eastern Africa. Although traditionally used for several applications, in vitro investigation of biological functions associated with Anthemis palestina essential oil had never been reported. METHODS The air-dried flowers of Anthemis palestina were subjected to hydrodistillation to yield the ...

Journal: :Alternatives to laboratory animals : ATLA 2010
Sarah Adler Gerd Bicker Hans Bigalke Christopher Bishop Jörg Blümel Dirk Dressler Joan Fitzgerald Frank Gessler Heide Heuschen Birgit Kegel Andreas Luch Catherine Milne Andrew Pickett Heidemarie Ratsch Irmela Ruhdel Dorothea Sesardic Martin Stephens Gerhard Stiens Peter D Thornton René Thürmer Martin Vey Horst Spielmann Barbara Grune Manfred Liebsch

An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET) at the Federal Institute for Risk Assessment (BfR), and took place on 27–28 April 2009, in Berlin, Germany. The goal of ZEBET is to promote p...

Journal: :International Journal of Enviornment and Climate Change 2022

Banana is parthenocarpic and vegetatively propagated crop due to which in vitro mutagenesis approaches have substantial scope create variations for improvement. Bhimkol cultivar a wild seeded type it set seeds naturally. The immature can be used the mutation variability. Prerequisite an study, determine appropriate dosages produce larger recovery of mutants with diminutive population loss. It n...

Journal: :Biomolecules 2021

Imuno TF® is a nutritional supplement composed of isolated transfer factors (TF) from porcine spleen. It specific mixture molecules that impact functions the biological systems and historically linked to immune system regulation. In this study, we demonstrate for first time its proteomic analysis, composition, safety profile in terms mutagenic potential acute oral dose (LD50). The obtained anal...

Background: Poisoning due to the bites and stings of venomous snakes and scorpions is a neglected public health problem, particularly in rural areas. Poor health facilities and inadequate knowledge of health care personnel are the major factors that result in envenomated human victims not receiving adequate care and medical attention. There is a great need for up-to-date and effective healthcar...

2010
Sarah Adler Gerd Bicker Hans Bigalke Christopher Bishop Jörg Blümel Dirk Dressler Joan Fitzgerald Frank Gessler Heide Heuschen Birgit Kegel Andreas Luch Catherine Milne Andrew Pickett Heidemarie Ratsch Irmela Ruhdel Dorothea Sesardic Martin Stephens Gerhard Stiens Peter D. Thornton René Thürmer Martin Vey Manfred Liebsch

An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET) at the Federal Institute for Risk Assessment (BfR), and took place on 27–28 April 2009, in Berlin, Germany. The goal of ZEBET is to promote p...

Journal: :Drug and chemical toxicology 2015
Peter E Rezk Pierre Zdenka Praveena Sabnekar Takwen Kajih David G Mata Chester Wrobel Douglas M Cerasoli Nageswararao Chilukuri

In this study, we determined the ability of recombinant human liver prolidase to hydrolyze nerve agents in vitro and its ability to afford protection in vivo in mice. Using adenovirus containing the human liver prolidase gene, the enzyme was over expressed by 200- to 300-fold in mouse liver and purified to homogeneity by affinity and gel filtration chromatography. The purified enzyme hydrolyzed...

2015
C. W. Paul A. E. Ligha

Carica papaya (Pawpaw) is a large herb that grows up to 6-9m in height, the seeds are small, black, ovoid and corrugated. Papain and chymopapain are among its biologically active compounds. The aim of the study was to determine the histologic effects of hydromethanol seed extracts of ripe carica papaya (HSEC) on wistar rats’ liver. The objectives were to determine: (a) the LD50 of HSEC. (b) The...

2013
Takashi MATSUMOTO

The negative effects of a commonly applied systemic insecticide, neonicotinoid, on the honey bee Apis mellifera L. are of great concern worldwide, as the use of the chemical is expanding. Recently, special attention has been paid to the sublethal effects of insecticides. An increasing number of studies has identified sublethal effects on the honey bee in the laboratory or in experimental cages,...

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