BACKGROUND & OBJECTIVES Treatment of inflammatory pain with opioids is accompanied by unpleasant and, at times, life-threatening side effects.Cannabis produces antinociception as well as psychotropic effects. It was hypothesized that peripheral cannabinoid receptors outside the central nervous system could be selectively activated for relief of pain. This study was undertaken to measure the ant...

Most recent studies discussing tachycardias with alternating QRS polarity have referred to those known as torsade de pointes. This report, in contrast, deals with bidirectional tachycardia and the effects of lignocaine on 10 patients with this arrhythmia. Three of the patients also had digitalis-induced atrial tachycardia with block. In one patient, a single bolus of lignocaine was followed (fi...

The study was undertaken to investigate a possible mechanism for reducing the phagocytosis of spermatozoa by leukocytes in the peritoneal fluid from women suffering from endometriosis. Peritoneal fluids were collected during laparoscopy from women undergoing laparoscopic sterilization or from women under investigation for cause of infertility where the laparoscopic findings were endometriosis. ...

To test the hypothesis that there would be a positive correlation between the interpeak wave (I-V) interval as measured by auditory brain stem evoked response and the ratio of umbilical cord blood arterial to venous lignocaine concentrations in infants born after maternal epidural anaesthesia, 10 normal infants born at full term by elective caesarean section were studied. Umbilical cord arteria...

The study aimed to ascertain the efficacy of oropharyngeal topical 10% lignocaine spray applied prior to induction of anaesthesia and also to determine the optimal time for spraying to attenuate pressor response to laryngoscopy and endotracheal intubation. 80 patients of either sex, in the age group of 20-60 years (ASA I & II) undergoing different elective surgical procedures under general anae...

The study was conducted on six geriatric dogs belonging to different breeds presented for various surgical procedures at the Veterinary hospitals of Kerala and Animal Sciences University, Mannuthy Kokkalai. Before undergoing anaesthesia, all underwent complete clinical examination pre-anaesthetic evaluation. All animals were administered a multimodal anaesthetic protocol with inj. dexmedetomidi...

Background: The myoclonus after induction of anesthesia with etomidate can lead to increased risk regurgitation and aspiration. We conducted this study compare the effectiveness midazolam lidocaine for prevention induced myoclonus.
 Methodology: This randomized controlled trial was done in Department Anesthesiology Intensive Care, Holy Family Hospital, Rawalpindi from January-June 2015 app...