the present treatment goals for inflammatory bowel diseases (ibd) especially ulcerative colitis (uc) include rapid induction of clinical remission, steroid-free maintenance of clinical remission, mucosal healing and improvement of quality of life in uc patients. immunomodulators have been reserved for steroid- dependent or steroid- refractory uc patients. among these agents, azathioprine/6-merc...

Methadone is widely being used for opioid substitution therapy. However, the administration of methadone to opioid dependent individual is frequently accompanied by withdrawal syndrome and chemical dependency develops. Other than that, it is also difficult to retain patients in the treatment programme making their retention rates are decreasing over time. This article is written to higlights th...

The effect of a chloroform soluble fraction (F-A) of the acetone extract of twigs of Sarcostemma brevistigma Wight on contractions induced by oxytocin and KCl, in the isolated rat uterine smooth muscles, has been evaluated. At concentrations of 32.8 μg/ml, the F-A significantly inhibited (P<0.001) the contractions induced by 60 mM KCl in Ca, containing physiological salt solution to the extent ...

Background: Substance abusers are not able to withdraw drugs eternally despite the abundance of different treatments; therefore, withdrawal programs are not quite successful and notwithstanding all the successes of methadone maintenance therapy, there are some defects found in the manner this treatment is applied. Thus, this study was conducted to explore the experience of drug abusers regardin...