introduction: the field of stem cell biology and regenerative medicine is rapidly moving toward translation to clinical practice. stem cell therapy seems to be a new treatment option for some diseases. so, tracking the distribution of stem cells is crucial to their therapeutic use. based on this fact we labeled human mesenchymal stem cells (mscs) with 111in- oxine for the first time in our coun...

The review discusses the pathogenetic mechanisms of development respiratory infection COVID-19 and clinical use cell technologies based on mesenchymal stem cells (MSCs). Due to global pandemic COVID-19/SARS-CoV-2 associated with spread SARS-CoV-2 virus, difficulty in treating severe cases infection, immunomodulatory activity MSCs due inflammatory microenvironment factors can be used complex tre...

The tissue engineering approach for periodontal regeneration using a combination of stem cells and scaffold has been vastly developed. Mesenchymal Stem Cells (MSCs) seeded with Bovine Teeth Scaffold (BTSc) can repair alveolar bone damage in periodontitis cases. process was analyzed by micro-computed tomography (µ-CT) to observe the structure growth visualize 3-Dimensional (3D). purpose this stu...

Atopic dermatitis (AD) is a chronic cutaneous inflammatory disease caused by an interaction between genetic, immune and epidermal barrier factors. Several treatments can be used to treat this but there are patients that do not respond actual drugs. So, need develop effective therapies for AD. Mesenchymal stem cells (MSCs) non-hematopoietic multipotent adult progenitor with immunomodulatory powe...

Mesenchymal stem cells (MSCs) isolated from dental tissues have also been studied extensively recently due to their relatively easy availability. The researchers working on improving a method for regenerating alveolar bone in patients with cleft lip and palate utilizing mesenchymal human marrow (hBMSCs). A systematic literature review 2010 2022 was performed using PubMed, Medline, ScienceDirect...

neuroinflammation has a significant role in induce of multiple sclerosis (ms) many approaches have been used to treat ms, but none of these methods have not been able to fully improve. one of the methods can suppress inflammation and regenerate the nervous system is the use of cell therapy. using cell therapy in pre-clinic phase can be realized, it's mechanism and potency to suppress neuro...

The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.In this study, we investigated the immunomodulatory effect of umbilical cord derived-mesenchymal stem cells (UC-MSCs) and bone marrow-derived-mesenchymal stem cells (BM-MSCs) on differentiation, maturation, and endocytosis of monocyt...

Neuroinflammation has a significant role in induce of Multiple sclerosis (MS) many approaches have been used to treat MS, but none of these methods have not been able to fully improve. One of the methods can suppress inflammation and regenerate the nervous system is the use of cell therapy. Using cell therapy in pre-clinic phase can be realized, it's mechanism and potency to suppress neuroinfla...