[reaction: see text] Here we describe a miniature protein (1) that presents the cAMP-dependent protein kinase (PKA) recognition epitope found within the heat-stable Protein Kinase Inhibitor protein (PKI) and a miniature protein conjugate (1-K252a) in which 1 is joined covalently to the high-affinity but nonselective kinase inhibitor K252a. Miniature protein 1 recognizes PKA with an affinity tha...

OBJECTIVE The Sonic Flashlight (SF) is a new handheld ultrasound (US) display device being developed at our institution. It replaces the standard monitor on a conventional ultrasound (CUS) system with a miniature monitor and half-silvered mirror to reflect real-time US images into the body. With the SF, the imaged body part appears translucent, with the US image appearing to float below the sur...

The instrument to be described was developed for the measurement of bioelectric potentials, especially those found on the skin. As such it was desired that it be portable, not dependent on the availability of electric current, and that, because of its biological applications, the input resistance be at least 10 megohms and that grid current through this resistance be less than 1 0-10 amperes wi...

Pottery art in Iran reached its apex during the Seljuk and Kharazmshahi eras. In these two periods, artists produced high-quality wares,with Minai decorations which were considered as masterpieces of Islamic art from an aesthetical point of view. These wares were decorated with motifs existing in manuscripts illustrated by artists from Baghdad and Seljuk miniature painting schools portraying ep...

Background: Ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. The mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown. We aimed to elucidate the effects of different concentrations of ketamine on the glutamatergic synaptic transmission of the neurons in the primary somatosensory cortex b...

human dental pulp inflammation can progress to periapical lesion formation and conventional root canal treatment (rct) has been the traditional method for disease management. this observational study presents two cases of vital pulp therapy in mature molars diagnosed with irreversible pulpitis and associated with apical periodontitis. in these two clinical cases, the involved teeth had deep car...

Epidermal melanocytes in mammals are known to occur in a variety of shapes, sizes, and colors. The basic melanocyte morphology is dependent upon genetics, but there are a number of environmental factors that can cause modification. In the epidermis of PET/\vrnr mice, the population of rnelanocytes reaches a peak and begins to decline during the first post-natal week, and has disappeared within ...

the aim of the present study was to determination the prevalence of gastric ulcer in caspian miniature horse. the design field- laboratorial study on 23 caspian miniature horses. feed withdraw 12-16 hours before study and the owners or riders completed a form about housing, medication, age, sex, cell boold counts and the biochemical profile tests were carried out. endoscope performed through th...

ome of the highlights of the ongoing program within the Sensor Science Group of APL’s Milton S. Eisenhower Research and Technology Development Center to develop novel magnetometers are summarized. In particular, two approaches are described: a magnetostrictive device based on the deflection of a Terfenol-D coated single-crystal silicon cantilever and a Lorentz-force device based on a classical ...