A new member of the connexin gene family has been identified and designated rat connexin-3 1 (Cx3 1) based on its predicted molecular mass of 30,960 daltons. Cx31 is 270 amino acids long and is coded for by a single copy gene. It is expressed as a 1.7-kilobase mRNA that is detected in placenta, Harderian gland, skin, and eye. Cx31 is highly conserved and can be detected in species as distantly ...

Staphylococcus aureus carrying PVL gene remain major health problem associated with highly virulent infections. Characterization of such gene is important to know the impact and the functional significance of nucleotide variations. PCR and standard sequencing were performed for twelve Sudanese strains from different sources. Protein structures prediction, modeling and physiochemical analysis we...

Abstract: Potato virus Y a type species of the genus potyvirus infects several crops in the family solanaceae. PVY isolated from field infected peppers was identified on the basis of host reaction, serological and molecular characterization. The result of ELISA, Immunoblot electrophoresis and Immuno Capture Reverse Transcription Polymerase Chain Reaction   (IC-RT-PCR) indicated that...

Human folate-binding proteins (FBPs) are single chain glycoproteins that contain a high affinity binding site for folates and methotrexate and occur in a soluble or membrane-associated form. The membrane-associated FBP is involved in the uptake of physiologic folates and methotrexate. In this study, human FBP cDNA clones were isolated from human malignant nasopharyngeal carcinoma (KB) cell and ...

background: cholesterol oxidase (cho) has various clinical and industrial applications. recently, microbial cho have received a great attention for their wide usage in medicine. here, taxonomic characterizations of isolated strain from soil, optimization of the conditions for cho production and biochemical characterizations of produced cho enzyme were described. finally, cho gene was cloned int...

this study was conducted to molecularly detect avian adenoviruses in broiler flocks showing liver lesions and respiratory syndrome in northeast iran. in total, 60 tissue samples were collected from broiler farms with liver lesions, respiratory syndrome and also from clinically healthy flocks. six samples were positive; however, three samples were selected for molecular studies. pcr products wer...

bacillus subtilis k40b was isolated from rice rhizospheres and its potential for production of xylanase was evaluated using biochemical methods. the gene for xylanase in b. subtilis k40b was amplified, sequenced and assigned to the ncbi genebank. the gene size was estimated to be 563 bp encoding 413 amino acids. comparison of the xylanase gene with reference sequences showed that the xylanase o...

Molecular imaging is the noninvasive visualization of normal as well as abnormal cellular processes at a molecular or genetic level of function. It is used to provide characterization and measurement of biological processes in living animals and humans (in vivo). The discipline of molecular imaging evolved rapidly over the past decade through the integration of cell biology, molecular biology a...