One of the most fundamental components of healthcare system on each country is blood supply chain management. This chain is comprised of two significant components including collecting donor’ bloods and supplying blood’s products. The main purpose of this paper is to concentrate on supplying blood products and present a novel constrained bi-objective mathematical model for a two-echelon blood s...

Platelet adhesiveness to glass was measured in healthy blood donors at the time of and eight days after donating 500 ml of blood. By a whole blood method a highly significant increase was found whereas by a method using platelet-rich plasma with added adenosine diphosphate there was only a slightly significant increase. The discrepancy suggested that changes in the red cell population might inf...

BACKGROUND Published analyses of clinical outcomes for patients requiring large-volume blood transfusion conflict with respect to the impact upon plasma potassium levels. We analyzed a cohort of trauma patients to ascertain the impact of component product transfusion upon plasma potassium values. METHODS We performed an observational analysis of previously, prospectively collected clinical da...

BACKGROUND We used sensitive spectroscopic techniques to measure changes in Band 3 oligomeric state during storage of packed red blood cells (RBC); these changes were compared to metabolic changes, RBC morphology, cholesterol and membrane protein loss, phospholipid reorganisation of the RBC membrane, and peroxidation of membrane lipid. The aim of the study was to temporally sequence major bioch...

Packed human red blood cells, diluted 1:1 with phosphate-buffered saline (PBS) containing 0-21% bovine serum albumin was used as a blood meal source for Anopheles farauti. Egg and larval production linearly increased with bovine serum albumin concentration in PBS. When the saline contained 9-21% bovine serum albumin, egg production was equivalent to that obtained when mosquitoes were fed direct...

Wheat grass juice is the juice extracted from the pulp of wheat grass and has been used as a general-purpose health tonic for several years. Several of our patients in the thalassemia unit began consuming wheat grass juice after anecdotal accounts of beneficial effects on transfusion requirements. These encouraging experiences prompted us to evaluate the effect of wheat grass juice on transfusi...

BACKGROUND The leading cause of late mortality after trauma is multiple organ failure syndrome, due to a dysfunctional inflammatory response early after injury. Preclinical studies demonstrate that hypertonicity alters the activation of inflammatory cells, leading to reduction in organ injury. The purpose of this study was to evaluate the effect of hypertonicity on organ injury after blunt trau...