objective: evidence shows that the powder/liquid mixing ratio recommended by the manufacturers is often not respected when mixing the glass ionomer (gi) powder and liquid, yielding a gi cement with disproportionate powder/liquid ratio. considering the confirmed effect of powder/liquid ratio on the gi properties, and more importantly, its fluoride release potential, this study aimed to assess th...

Perchlorate is a widespread contaminant in the United States.1 Research has demonstrated its presence in various media, including water, soil, various foods, and also human biological fluids, such as urine and breast milk.2-6 Perchlorate causes an adverse health effect by competitively inhibiting iodide uptake by the thyroid gland because it exhibits a much higher selectivity factor than iodide...

Perchlorate contamination of aquifers and drinking-water supplies has led to stringent regulations in several states to reduce perchlorate concentrations in water at acceptable levels for human consumption. Several perchlorate treatment technologies exist, but there is significant cost associated with their use, and the majority of them are unable to degrade perchlorate to innocuous chloride. W...

Perchlorate (ClO4) has been detected in some states in the U.S and become an environmental concern since the late 1990’s. Perchlorate properties, contamination, and health effects were introduced in this paper. Perchlorate biodegradation degradation were introduced and summarized. According to recent studies, perchlorate respiring bacteria are present in natural environments, providing possibil...

Exposure to perchlorate is ubiquitous in the United States and has been found to be widespread in food and drinking water. People living in the lower Colorado River region may have perchlorate exposure because of perchlorate in ground water and locally-grown produce. Relatively high doses of perchlorate can inhibit iodine uptake and impair thyroid function, and thus could impair neurological de...

Perchlorate blocks thyroidal iodide transport in a dose-dependent manner. The human sodium/iodide symporter (NIS) has a 30-fold higher affinity for perchlorate than for iodide. However, active transport of perchlorate into thyroid cells has not previously been demonstrated by direct measurement techniques. To demonstrate intracellular perchlorate accumulation, we incubated NIS-expressing FRTL-5...