Severe, sustained pulmonary hypertension leads to pulmonary vascular obstructive disease, which is potentially fatal. But recent advances in genetics and cell biology provide insights into the pathogenesis of this disease and new treatments offer an improved quality of life and increased survival. The field is moving rapidly, and it is time to adopt a more positive and aggressive approach to th...

background: respiratory distress syndrome and persistent pulmonary hypertension of the newborn are common acquired diseases in preterm infants. in the past several years, randomized controlled trials (rcts) have indicated that inhaled nitric oxide (ino) can potentially lower for both the incidence of bronchopulmonary dysplasia (bpd) and mortality in affected infants. other research has, however...