Neonates with pulmonary atresia and intact interventricular septum (PAIVS) do not have pulmonary vascular disease secondary to their heart abnormality. Persistent pulmonary hypertension of the newborn has not been described in association with this condition. The case is reported of a female neonate born with PAIVS, who preoperatively had no clinical evidence or any risk factors for persistent ...

OBJECTIVE To examine the risk for persistent pulmonary hypertension of the newborn associated with antenatal exposure to antidepressants. DESIGN Systematic review and meta-analysis. DATA SOURCES Embase, Medline, PsycINFO, and CINAHL from inception to 30 December 2012. ELIGIBILITY English language studies reporting persistent pulmonary hypertension of the newborn associated with exposure t...

BACKGROUND Persistent pulmonary hypertension is a well-known disease of the newborn that in most cases responds well to treatment with nitric oxide and treatment of any underlying causes. Genetic causes of persistent pulmonary hypertension of the newborn are rare. The TWIST1 gene is involved in morphogenetics, and deletions are known to cause Saethre-Chotzen syndrome. Deletions of PHF14 have ne...

Neonates with pulmonary atresia and intact interventricular septum (PAIVS) do not have pulmonary vascular disease secondary to their heart abnormality. Persistent pulmonary hypertension of the newborn has not been described in association with this condition. The case is reported of a female neonate born with PAIVS, who preoperatively had no clinical evidence or any risk factors for persistent ...

OBJECTIVES To evaluate risks for persistent pulmonary hypertension in the newborn, confirmed by echocardiography, associated with cesarean deliveries and other factors. METHODS Cohort of all deliveries >36 weeks within a period of 23 months. A nested case-control study was performed in a subset of the cohort, involving newborns admitted into neonatal intensive care unit with diagnosis of pers...

Persistent pulmonary hypertension of the newborn is a disorder with failure to decrease pulmonary vascular resistance after birth. Persistent pulmonary hypertension of the newborn happens in one out of 500 live births with a mortality rate 10-50%. Right after birth the pulmonary vascular resistance decreases drastically within a few minutes when oxygen enters into the fluid-filled alveoli. Fail...