نتایج جستجو برای: pharmacologic pain

تعداد نتایج: 264416  

Journal: :Pain 2007
Robert H Dworkin Alec B O'Connor Miroslav Backonja John T Farrar Nanna B Finnerup Troels S Jensen Eija A Kalso John D Loeser Christine Miaskowski Turo J Nurmikko Russell K Portenoy Andrew S C Rice Brett R Stacey Rolf-Detlef Treede Dennis C Turk Mark S Wallace

Patients with neuropathic pain (NP) are challenging to manage and evidence-based clinical recommendations for pharmacologic management are needed. Systematic literature reviews, randomized clinical trials, and existing guidelines were evaluated at a consensus meeting. Medications were considered for recommendation if their efficacy was supported by at least one methodologically-sound, randomize...

Journal: :Archives of Physical Medicine and Rehabilitation 2010

2017
Paul F White Ofelia Loani Elvir Lazo Lidia Galeas Xuezhao Cao

The use of opioid analgesics for postoperative pain management has contributed to the global opioid epidemic. It was recently reported that prescription opioid analgesic use often continued after major joint replacement surgery even though patients were no longer experiencing joint pain. The use of epidural local analgesia for perioperative pain management was not found to be protective against...

Journal: :Annals of internal medicine 2004
Clifford J Woolf

Pain is a multidimensional sensory experience that is intrinsically unpleasant and associated with hurting and soreness. It may vary in intensity (mild, moderate, or severe), quality (sharp, burning, or dull), duration (transient, intermittent, or persistent), and referral (superficial or deep, localized or diffuse). Although it is essentially a sensation, pain has strong cognitive and emotiona...

Journal: :Journal of dental education 2001
R A Dionne

The management of chronic orofacial pain often follows a pattern of claims of efficacy based on clinical observations superseded by equivocal findings of effectiveness or belated recognition of toxicity. While therapeutic innovation spurred by genomics and proteomics is likely to result in new drugs for pain, inflammation, and neuropathic pain, the process of drug development and approval takes...

Journal: :Anesthesia and analgesia 2016
Honorio T Benzon Spencer S Liu Asokumar Buvanendran

Journal: :Pediatrics 2008
William T Zempsky

A variety of pharmacologic options are available to clinicians who want to provide effective and safe topical local anesthesia to children undergoing venous access procedures. These options can be distinguished on the basis of how they deliver active drug through the impermeable outer layer of skin, the stratum corneum, to pain receptors located in the dermis and epidermis. Three general method...

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