BACKGROUND With the properties of three-column fixation and anterior-approach-only procedure, anterior transpedicular screw (ATPS) is ideal for severe multilevel traumatic cervical instabilities. However, the accurate insertion of ATPS remains challenging. Here we constructed a patient-specific biocompatible drill template and evaluated its accuracy in assisting ATPS insertion. METHODS After ...

objective(s): the aim of this work was to investigate the effect of the natural and the chemically modified form of cyclodextrins namely; β-cyclodextrin (β-cd) and hydroxypropyl-β-cyclodextrin (hp-β-cd) respectively on the solubility and dissolution rate of aripiprazole; an antipsychotic medication showing poor aqueous solubility.   materials and methods: phase solubility of aripiprazole with t...

We propose a unique process to generate non-spherical hydrogel microstructures using an aqueous two-phase system (ATPS) in a non-equilibrium state. A dextran (Dex) solution containing cells and hydrogel precursor (sodium alginate; NaA) was introduced into microfabricated chambers, which was gradually shrunk and deformed after pouring a polyethylene glycol (PEG) solution. Following the addition ...

BACKGROUND Biological effects of extra-low-frequency (ELF) magnetic fields (MFs) have lacked a credible mechanism of interaction between MFs and living material. OBJECTIVES To examine the effect of ELF-MFs on cancer cells. METHODS Five cancer cell lines were exposed to ELF-MFs within the range of 0.025-5 µT, and the cells were examined for karyotype changes after 6 d. RESULTS All cancer c...

Die Arbeitstagung Programmiersprachen (ATPS) ist eine jährlich stattfindende Veranstaltung der Fachgruppe Programmiersprachen und Rechenkonzepte der Gesellschaft für Informatik (GI). Sie dient dem Austausch zwischen Wissenschaftlern, Entwicklern und Anwendern, die sich mit Themen aus dem Bereich der Programmiersprachen beschäftigen. Dabei sind alle Programmierparadigmen gleichermaßen von Intere...

Currently, triple phase-shift (TPS) modulation has attracted more and attention of researchers as an advanced strategy for dual active bridge converter (DAB). Since it three degrees freedom, can realize better performance both in soft switching ranges power efficiency. However, how to choose these freedom optimal efficiency DAB becomes a concern researchers. Generally, there exist two difficult...

In this work liquid-liquid equilibrium for aqueous two phase system composed of polyethylene glycol di-methyl ether and tri-potassium citrate at different medium pH values (6.00, 7.00 and 8.00) and 298.15 K was studied. The obtained results show that two phase area expanded with an increasing of pH values. The performances of the Merchuk and semi-empirical equations were tested in correlating t...

Extracellular vesicles (EVs) such as exosomes and microvesicles released from cells are potential biomarkers for blood-based diagnostic applications. To exploit EVs as diagnostic biomarkers, an effective pre-analytical process is necessary. However, recent studies performed with blood-borne EVs have been hindered by the lack of effective purification strategies. In this study, an efficient EV i...

We present a simple and rapid method to isolate extracellular vesicles (EVs) by using a polyethylene glycol/dextran aqueous two-phase system (ATPS). This system isolated more than ~75% of melanoma-derived EVs from a mixture of EVs and serum proteins. To increase the purity of EVs, a batch procedure was combined as additional steps to remove protein contaminants, and removed more than ~95% of th...

We present the light scattering properties of individual human red blood cells (RBCs). We show that both the RBC static and dynamic scattering signals are altered by adenosine 5'-triphosphate (ATP)-driven membrane metabolic remodeling. To measure the light scattering signal from individual RBCs, we use diffraction phase microscopy together with a Fourier transform light scattering technique. RB...