absrtact   aim and background: autistic traits may present in normal population without interfering with daily functionings. the present investigation is to find factor structure and validation of broad autism phenotype questionaire (bapq) and comparing psychometric structures of it with autsim quotient (aq). methods and materials: in this correlational study, 351 students in shahid beheshti un...

multidrug resistance (mdr) is a complex phenomenon in which many different genes regulating drug transport, cellular repair, detoxification and drug metabolism are involved. nevertheless, in most drug resistant cell lines and cancer patients up-regulation of abc-transporter genes such as mdr associated protein (mrp1) gene could be at the basis of the drug resistance phenotype. we aimed to decre...

drug resistance enables cancer cells to break away from cytotoxic effect of anticancer drugs. identification of resistant phenotype is very important because it can lead to effective treatment plan. there is an interest in developing classifying models of resistance phenotype based on the multivariate data. we have investigated a vibrational spectroscopic approach in order to characterize a sen...

Deep phenotyping is defined as learning about genotype-phenotype associations and the history of human illness by analyzing phenotypic anomalies. It significant to investigate association between phenotype genotype. Machine approaches are good at predicting abnormal phenotypes genes. A novel framework based on machine proposed estimate links ontology (HPO) The Orphanet’s annotation parses pheno...