oxidative stress is involved in the pathogenesis of asthma. paraoxonase 1 (pon1) and arylesterase are esterase enzymes displaying antioxidant characteristics. pon1 activity varies widely among individuals and ethnic groups, partly related to polymorphisms. the aim of this study was to determine the activities of pon1 and arylesterase including the phenotype distribution of pon1 in asthmatic pat...

background: generation of an effective dendritic cell (dc) based cancer vaccine depends on appropriate differentiation of monocytes in vitro. objective: to compare the effects of monocyte separation methods, flask adherence (flask-dc) and magnetic activated cell sorting (macs-dc), on phenotypic and functional characteristics of resultant dcs. methods: dcs from healthy volunteers were generated ...

the aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. in a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. demographic, clinical, and familial history were compared between two groups. there was no significant differences between variables like sex, age of onset ...

landmark based geometric morphometrics and comparison of meristic characters was used to understand potential differences between populations of waspi in mashkil and mokran basins. 97 specimens of waspies were caught (64 from mashkil river and 33 from sarbaz river). 14 landmarks were digitized on pictures taken from left side of specimens and meristic characters were counted. data were analyzed...

background:there is no comprehension data on anatomicalindices of nigerian goats. objectives: to show osteometricvalues of some cranial indices in nigerian goats. methods:sixty (60) goat skulls that were found around makurdi, kwande,katsina-ala and the neighbouring adamawa state of nigeria,were studied by investigating the 30 craniometric values.results: the measured distance from the facial tu...

introduction dendritic cells (dcs) are bone marrow-derived cells, which migrate to lymphoid and non-lymphoid organs via blood. liver dcs are believed to play an important role in the regulation of hepatic allograft acceptance. however, because of inherent difficulties in isolating adequate numbers of dcs from liver, limited information is available on the phenotype and functions of liver dcs. t...

cystic fibrosis is an autosomal recessive disease caused by a wide spectrum of mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator protein. these mutations that correlate with different phenotypes, vary in their frequency and distribution in different populations. in this study missense mutation r117h that associated with the different clinical symptoms wa...

background: cyp2d6 is polymorphically expressed enzyme that show marked interindividual and interethnic variation. phenotyping of cyp2d6 provides valuable information about real-time activity of this important drug-metabolizing enzymes through the use of specific probe drugs. the aim of this study was to identify the cyp2d6 oxidation phenotype with dextromethorphan (dex) as a probe drug in maza...

morphological, biochemical and molecular characteristics were studied to identify dominant lactic acid bacteria (lab), isolated from traditional yoghurts produced by tribes of iran. from 60 yoghurt samples, a total of 137 lab isolates were determined, in which 66 and 71 were identified as lactic acid cocci and bacilli, respectively. biochemical tests showed the occurrence of 9.76% mesophilic ho...

Background and Objectives: Staphylococcus aureus is an important cause of nosocomial and community-acquired infections in every region of the world. Clindamycin is one of the alternative agents used to treat S. aureus infections and accurate identification of clindamycin resistance is important to prevent therapeutic failure. Unfortunately, inducible clindamycin resistance is ...