Aseries of piperidine derivatives was synthesis by the reaction between substituted benzaldhyde ,pentanone-3,and ammonium acetate by refluxining for 1-2 hr in ethanol and the derivatives refluxed with (4,4'-Diaminodiphenyl sulphone) yielded bispiperidine ,the structures of the synthesized compounds were confirmed by spectroscopy analysis , The reported compounds were screened for their antibact...

Phencyclidine (1-(1-phenylcyclohexyl) piperidine, PCP, I) and ketamine (2-O-chlorophenyl-2-methylaminocyclohexan, II) have shown analgesic effects. Some of its derivatives were synthesized and their biological properties have been studied. In this study, a new derivative of PCP, (1-[1-(3-methoxyphenyl) (tetralyl)] piperidine, PCP-OCH3-tetralyl, III) was synthesized and the acute thermal pain ...

phencyclidine (1-(1-phenylcyclohexyl) piperidine, pcp, i) and ketamine (2-o-chlorophenyl-2-methylaminocyclohexan, ii) have shown analgesic effects. some of its derivatives were synthesized and their biological properties have been studied. in this study, a new derivative of pcp, (1-[1-(3-methoxyphenyl) (tetralyl)] piperidine, pcp-och3-tetralyl, iii) was synthesized and the acute thermal pain of...

Introduction. The search for new, effective and safe pharmacologically active substances remains an urgent task in the field of pharmacy. Many compounds piperidine morpholine series are widely used medical practice belong to important group biologically compounds. An informational, literature on synthesis new derivatives was carried out. article summarizes results studies as potential sources s...

Abstract: Piperidine alkaloids are members of the alkaloid family that is characterized by presence a six-membered nitrogen-containing heterocycle. found mainly in plants and often exhibit interesting biological pharmacological activities. Despite accumulation these natural products plants, relatively low quantities produced absolute terms thus synthesis derivatives thereof remains relevant to ...

In the title tetra-nuclear compound, [Cu4(C7H14NO)4Cl4], each Cu(II) cation is N,O-chelated by a piperidineethanolate anion and coordinated by a Cl(-) anion and two O atoms from neighboring piperidine-ethano-late anions in a distorted NO3Cl square-pyramidal geometry. The deprotonated hydroxyl groups of the piperidineethanolate anions bridge Cu(II) cations, forming the tetra-nuclear complex. All...