Calcium is a universal intracellular signaling molecule. Through variations in both the amplitude and frequency of intracellular calcium increases, the same calcium ion can elicit different responses. In this report, we investigated the effect of a calcium transient, lasting 2-5 min, on alterations in the phosphorylation state of the cytoskeletal protein, tau. Transient increases in calcium res...

It has been shown repeatedly (14) that in cardiac and renal disease, both in adults and children, there is a direct relationship between the levels of serum protein and serum calcium, and also, within limits, an inverse relationship between the serum inorganic phosphorus and the serum calcium (l-5). Peters and Eiserson (4) attempted a mathematical evaluation of the relative effects of protein a...

An in vitro system was devised for studying phosphorylation of Chlamydomonas reinhardtii axonemal proteins. Many of the polypeptides phosphorylated in this system could be identified as previously described axonemal components that are phosphorylated in vivo. The in vitro system apparently preserved the activities of diverse axonemal kinases without greatly altering the substrate specificity of...

background: pregnancy is associated with unfavorable metabolic profile, which might in turn result in adverse pregnancy outcomes. the current study was designed to evaluate the effects of calcium plus vitamin d administration on metabolic status and pregnancy outcomes in healthy pregnant women. methods: this randomized double‑blind placebo‑controlled clinical trial was performed among 42 pregna...

Introduction: The neurotoxic effects of aluminum exposure during the critical period of neurodevelopment have been well documented. This study investigated the known protective effects of calcium supplementation on the cerebellum of juvenile Wistar rats following aluminum-induced neurotoxicity during lactation. Methods: Four groups of juvenile rats were exposed via lactation to distilled water...