نتایج جستجو برای: q22
تعداد نتایج: 928 فیلتر نتایج به سال:
In t(8;21)(q22;q22) acute myeloid leukemia, the prognostic value of early minimal residual disease assessed with real-time quantitative polymerase chain reaction is the most important prognostic factor, but how long-term minimal residual disease monitoring may contribute to drive individual patient decisions remains poorly investigated. In the multicenter CBF-2006 study, a prospective monitorin...
Fig. 1. G-banded karyogram from the patient’s bone marrow. Arrows indicate a t(1;8)(p36;q22). The t(8;21) translocation occurs in 5e12% of acute myeloid leukemia (AML) cases, often occurring in the younger population. This translocation fuses the RUNX1 gene (previously AML1) on chromosome band 21q22 to the RUNX1T1 (previously known as ETO) on 8q22, resulting in a RUNX1/RUNX1T1 hybrid transcript...
Expression of B Cell–Specific Activator Protein/PAX5 in Acute Myeloid Leukemia With t(8;21)(q22;q22)
Motivated by the remarkably narrow range of measured spin frequencies of ∼ 20 accreting (and weakly magnetic) neutron stars in the Galaxy, Bildsten (1998a) conjectured that their spin-up had been halted by the emission of gravitational waves. If so, then the brightest persistent X-ray source on the sky, Scorpius X-1, should be detected by gravitational wave interferometers within ten years. Bil...
OBJECTIVES To assess the frequency of systemic mastocytosis (SM) in a large series of acute myeloid leukemia (AML) with t(8;21)(q22;q22). METHODS We retrospectively characterized 40 bone marrow aspirate smears and biopsy specimens from patients with AML with t(8;21) for the presence of SM. Cases were assessed for mast cell morphology and immunohistochemistry, as well as KIT exon 8 and 17 muta...
BACKGROUND Several studies of pediatric acute myeloid leukemia have described the various type-I or type-II aberrations and their relationship with clinical outcome. However, there has been no recent comprehensive overview of these genetic aberrations in one large pediatric acute myeloid leukemia cohort. DESIGN AND METHODS We studied the different genetic aberrations, their associations and t...
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