Autoimmune responses were observed in a large proportion of hepatitis C cases and are suspected to be part of viral pathogenesis. The AN6520 antigen (AN-Ag) is a normal cellular protein mainly expressed in liver that was found associated with non-A, non-B hepatitis. To elucidate its pathogenic role in hepatitis C, we developed an IgM capture assay using purified AN-Ag and confirmed that the ant...

The capacity of the testis to metabolize xenobiotics has been proposed to play a role in the susceptibility of different species to testicular toxicity. Since species differences in testicular xenobiotic metabolizing enzyme activities are not well documented, the primary objective of the present study was to compare enzyme activities in subcellular fractions prepared from rat, mouse, monkey, an...

Human microsomal epoxide hydrolase (mEH), encoded by the EPHX1 gene, is involved in the metabolism of tobacco carcinogens. We investigated the effect of exon 3 and 4 polymorphisms of the EPHX1 gene in 121 patients with cancers of the oral cavity/pharynx, 129 patients with cancer of the larynx, and 172 non-cancer controls, all Caucasian regular smokers. The potential modifying role of previously...

Photophysical processes in conjugated polymers are influenced by two competing effects: the extent of excited state delocalization along a chain, and the electronic interaction between chains. Experimentally, it is often difficult to separate the two because both are controlled by chain conformation. Here we demonstrate that it is possible to modify intra-chain delocalization without inducing i...

OBJECTIVES Multifocal epithelial hyperplasia (MEH) is benign, asymptomatic oral disease with viral etiology. The frequency of this disease varies widely from one geographic region to another, and can vary, from 0.002 to 35% depending on the population studied. STUDY DESIGN Here we report the clinicopathological features of twelve cases of MEH referred to Oral Medicine Department of Mashhad De...

OBJECTIVES To investigate neurobehavioural effects and the persistence of complaints in workers exposed to styrene relative to exposure characteristics and the enzyme microsomal epoxide hydrolase (mEH) activity. METHODS A cross sectional study was performed in a retrospective cohort of workers of a polyester boat building plant 3 years after the main activity shut down in 1989. Workers still ...

The primary objective of desalination research is the development of a way to produce fresh water at lower cost. The present study investigated two freshwater production methods of Reverse Osmosis (RO) and Multi-Effect Humidification (MEH) (artificial distillation), and analyzed them from an economic standpoint, and subsequently pointed out the important and effective factors in decreasing salt...

We report the observations of dual wavelength amplified spontaneous emission from the solutions of a conjugated polymer poly [2-methoxy-5-(2-ethylhexyloxy)-1, 4-phenylenevinylene] (MEH-PPV) in Tetrahydrofuran and 1, 2 Dichlorobenzene. We have prepared MEH-PPV using a modified procedure and purified several times in each step, the material offers low molecular weight, low polydispersity index an...

We report on the device physics of nanostructured amorphous-silicon a-Si:H /polymer hybrid solar cells. Using two different polymers, poly 3-hexylthiophene P3HT and poly 2-methoxy-52 -ethyl-hexyloxy -1,4-phenylenevinylene MEH-PPV , we study the exciton diffusion, charge transfer, and charge-carrier transport in bilayer and nanostructured a-Si:H/polymer systems. We find that strong energy transf...