Microsomal epoxide hydrolase (mEH) plays a significant role in the metabolism of numerous xenobiotics and is associated with several forms of cancer. Here, we investigated the role of mEH expression in bladder carcinogenesis, subsequent progression and recurrence. The expression of mEH was analyzed by Western blot in 50 bladder urothelial carcinoma and 20 normal epithelial tissues. There was a ...

A pesar del avance reciente de los estudios sobre glaciarismo y periglaciarismo en las Montañas Cantábricas, el foco investigaciones se ha puesto conjuntos mayor altitud, mientras áreas como sector centro-occidental la montaña asturiana han recibido menor atención. En este ámbito, Puerto Ventana constituye un área paradigmática debido a sus características altimétricas litoestratigráficas. estu...

Microsomal epoxide hydrolase (mEH) plays an important role in the detoxification of a broad range of epoxide intermediates and has been reported to be decreased during diabetes and fasting. The signaling pathways involved in the regulation of mEH expression in response to insulin and glucagon were examined in primary cultured rat hepatocytes. mEH protein levels were increased 2- to 6-fold in he...

The microsomal epoxide hydrolase (mEH) plays a significant role in the metabolism of xenobiotics such as polyaromatic toxicants. Additionally, polymorphism studies have underlined a potential role of this enzyme in relation to a number of diseases, such as emphysema, spontaneous abortion, eclampsia, and several forms of cancer. We recently demonstrated that fatty amides, such as elaidamide, rep...

Genetic polymorphisms of microsomal epoxide hydrolase (mEH) have been associated with increased risk of lung cancer. However, expression of mEH and its clinical significance in non-small cell lung cancer (NSCLC) have not been investigated. In this study we investigated the expression and genetic polymorphism of mEH in non-small cell lung cancer (NSCLC) patients. Genetic polymorphism was determi...

BACKGROUND Hepatocarcinogenesis is a complex process that may be influenced by many factors, including polymorphism in microsomal epoxide hydrolase (mEH). Previous work suggests an association between the Tyr113His and His139Arg mEH polymorphisms and susceptibility to hepatocellular carcinoma (HCC), but the results have been inconsistent. METHODS PubMed, EMBASE, Google Scholar and the Chinese...

Single chains of conjugated polymers e.g. MEH-PPV (poly(2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylenevinylene) have become interesting objects for single molecule spectroscopy (SMS) studies. However, most of the experiments so far were performed without full awareness of the isolation status of the polymer chains in host matrices. We used steady-state and time-resolved fluorescence methods and 2...

The charge photogeneration and early recombination in MEH-PPV-based charge-transfer complexes (CTCs) and in MEH-PPV/PCBM blend as a reference are studied by ultrafast visible-pump-IR-probe spectroscopy. After excitation of the CTC band, an immediate (<100 fs) electron transfer is observed from the polymer chain to the acceptor with the same yield as in the MEH-PPV/PCBM blend. The forward charge...

This paper investigates the synthesis processes for poly(3-octylthiophene) (P3OT) and poly[2-methoxy-5-(2 0-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV). The proton nuclear magnetic resonance (H NMR) and the Fourier transform infrared spectrophotometer (FTIR) were used to identify the chemical structure and functional group of synthesized polymers, respectively. The efficient Förster energy ...

native phosphate solubilizing bacteria (psb) were isolated from four areas (ankober, keyt, mehalmeda and molale) of ethiopia to study their effect on releases of soluble phosphorus from insoluble p sources. the highest bacterial number was found at keyt (2.6103 g-1soil) and the least at molale (15 g-1soil). five efficient psb were selected for further study based on their ability in forming a ...