objective: methicillin-resistant staphylococcus aureus is a major cause of nosocomial and community-acquired infections. aminoglycosides are potent bactericidal agents that are often used in combination with either a β-lactam or a glycopeptide, especially in the treatment of staphylococcal endocarditis. the main mechanism of aminoglycoside resistance in staphylococci is drug inactivation by cel...

conclusions the findings of the present study well demonstrated that the p. aeruginosa biofilm-producing isolates were more resistant to the tested antibiotics. furthermore, because of wide distribution, it seems that the psla gene is associated with biofilm formation. results biofilm formation was observed in 70% of the p. aeruginosa isolates. the potential formation of biofilm was significant...

appearance of bacteria resistant to antibacterial agents puts physicians in trouble and threatens the health of the world. the rapid development of bacterial resistance in escherichia coli to ciprofloxacin makes difficult the treatment of infectious diseases. so, detection of the locations of possible mutations in gyrase a gene ( gyra ) in these mutants is very important to determine the mechan...

background and objective: nowadays, the presence of extended-spectrum β-lactamases (esbls) producing strains in serratia genus causes the emergence of resistance to many antibiotics. so, the lack of proper diagnosis of esbls strains can lead to failure in the treatment. the objective of the present study was to investigate esbls production in serratia strains isolated from the clinical blood sa...

background assessment of resistance genes is imperative, as they become disseminated to bacterial flora in plants and to the indigenous bacterial community, and thus ultimately contributes to the clinical problems of antibiotic resistant pathogens. objectives the research was to assess the antibiotic characteristics and incidence of sul3 genes of stenotrophomonas maltophilia isolates recovered ...

introduction: the major resistance mechanisms of pseudomonas aeruginosa to fluoroquinolones and carbapenems are associated with the mutations in the genes gyra and oprd encoding type ii topoisomerases (dna gyrase) and oprd porin, respectively. method: in this cross-sectional study, sixty five clinical samples were collected from patients hospitalized in al-zahra hospital of isfahan, iran. susce...

conclusions the results showed that e. coli isolated from patients with uti had eight virulence factors with high frequencies. moreover, these results alleged a direct connection between virulence factors and antimicrobial resistance in e. coli. results the frequency of virulence factors papc, afa, sfa/foc, fimh, hly, neuc, ibea, and iucc were 53.3%, 51.7%, 53.3%, 56.7%, 23.3%, 31.7%, 20%, and ...