BACKGROUND: All-trans retinol is a biological antioxidantscavenging the ROS in the cell culture. OBJECTIVES: This studywas conducted to investigate the effect of all-trans retinol infertilization and culture medium on mouse embryo's developmentalcompetence. METHODS: This study was designed into twoexperiments. In the first experiment, in vitro mature oocytes wereco-cultured with sperm in fertil...

Exposure to toxic levels of fatty acids (lipotoxicity) leads cell damage and death is involved in the pathogenesis metabolic syndrome. Since consequences lipotoxicity are still poorly understood, we studied bioenergetic effects saturated acid palmitate, quantifying changes mitochondrial morphology, real-time oxygen consumption, ATP production sources, extracellular acidification hepatoma cells....

Background: Activation of the unfolded protein response (UPR) is closely related to pathogenesis many metabolic disorders. Accumulating evidence also shows that UPR and signaling pathways are interdependent. The AMP-activated kinase (AMPK) signal pathway controls energy balance eukaryotes. aim this study was therefore investigate possible interaction between AMPK in muscle cells exposed saturat...

Chronic ethanol consumption reduces the liver retinoid store in man and rat. We have studied the effect of ethanol on some aspects of retinoid metabolism in parenchymal and nonparenchymal liver cells. Rats fed 36% of total energy intake as ethanol for 5-6 weeks had the liver retinoid concentration reduced to about one-third, as compared to pair-fed controls. The reduction in liver retinoid affe...

Amaç: Retinol fetusta birçok organın gelişimi için gereklidir. Bu nedenle retinol eksikliği teratojenik etkilere neden olabilir. çalışmada çok düşük doğum ağırlıklı bebeklerde retinol, bağlayıcı protein (RBP) ve plasental transfer hızı düzeyleri ile prematüre retinopatisi (ROP) arasındaki ilişkiyi araştırmayı amaçladık. Gereç Yöntemler: Çalışma ocak-aralık 2020 tarihleri arasında prospektif koh...

background: oxidative stress in reproductive system leads to sperm dna damage and sperm membrane lipid peroxidation and may play an important role in the pathogenesis of male infertility, especially in idiopathic cases. antioxidants such as carotenoids function against free radical damages. objective : the aim of this study was to determine the levels of lycopene, beta-carotene and retinol in s...

Vitamin A is the generic name given to a group of fat-soluble compounds including retinol (the alcohol form), retinyl esters, retinaldehyde and retinol acid. Deficiency, first recognized in 1912, can damage the epithelial cells lining the respiratory tract. It can also affect immunocompetence, the reproductive function, growth and vision. The dose of vitamin A for neonates is 5,000 IU given int...

The metabolism of palmitate by polymorphonuclear leukocytes (PMN) from guinea pig exudate in the presence of physiological concentrations of human serum albumin has been studied. The data indicate that with increasing concentration of palmitate in the medium (over a range of 0.54 to 5.4 pmoles/ml), there is a concomitant increase in uptake of oxygen and palmitate. The RQ decreased from 1.34 to ...