The quest to create superhard materials rarely strays from the use of high-pressure synthetic methods, which typically require gigapascals of applied pressure. We report that rhenium diboride (ReB2), synthesized in bulk quantities via arc-melting under ambient pressure, rivals materials produced with high-pressure methods. Microindentation measurements on ReB2 indicated an average hardness of 4...

The possibility of selective leaching process was investigated during molybdenite flue dust leaching to recover its rhenium content. The results show that addition of alcohols to water makes the medium less favorable for molybdenum transfer into aqueous phase. On the other hand, addition of small amounts of alcohols (5-15%) makes a noticeable separation of rhenium over molybdenum, but by increa...

Pain management would be greatly enhanced by a formulation that would provide local anesthesia at the time desired by patients and with the desired intensity and duration. To this end, we have developed near-infrared (NIR) light-triggered liposomes to provide on-demand adjustable local anesthesia. The liposomes contained tetrodotoxin (TTX), which has ultrapotent local anesthetic properties. The...

Doxorubicin (Dox) loaded thermosensitive liposomes (TSLs) have shown promising results for hyperthermia-induced local drug delivery to solid tumors. Typically, the tumor is heated to hyperthermic temperatures (41-42 °C), which induced intravascular drug release from TSLs within the tumor tissue leading to high local drug concentrations (1-step delivery protocol). Next to providing a trigger for...

Abstract The paper deals with the study of rhenium recovery by AMR anionite from model high-acidic sulfuric solution as well its desorption ammonia in column experiments. Total dynamic exchange capacity was calculated. Experimental data were processed using Thomas, Yoon-Nelson and Bed Depth Service Time models, basic parameters It found that total calculated Thomas fit closest to experimental v...

Liposomes constitute one of the most popular nanocarriers for improving the delivery and efficacy of agents in cancer patients. The purpose of this study was to design and evaluate immunoliposome co-delivery of bufalin and anti-CD40 to induce synergetic therapeutic efficacy while eliminating systemic side effects. Bufalin liposomes (BFL) conjugated with anti-CD40 antibody (anti-CD40-BFL) showed...

BACKGROUND The objective of this study was to compare the transfection efficiency of anionic liposomes coated with polyethylenimine (PEI) with that of PEI and Lipofectamine 2000(™) using the plasmid DNA encoding green fluorescent protein in a human hepatoma (Huh7) cell line. METHODS Factors affecting transfection efficiency, including type of surfactant, ratio of phosphatidylcholine (PC)/surf...

Hepatocellular carcinoma (HCC) is the most common primary liver tumor and one of the fifth most common tumors worldwide. In this article we report the results of in vivo studies of potential anticancer agent "[188Re] rhenium-ImDendrim" derived from [188Re]rhenium-nitro-imidazole-methyl -1,2,3-triazol-methyl-di-(2-pycolyl)amine as radioactive ligand loaded 5th generation poly-L-lysine denrimer (...