Clinicians commonly sedate critically ill patients. Sedatives should be administered to achieve predetermined end points. Most currently available scales used to assess sedation are inadequate because they focus on a single domain, such as consciousness. The development of the American Association of Critical-Care Nurses' Sedation Assessment Scale is described. This new scale consists of 5 doma...

Актуальність. На сьогодні роль магнію в лікуванні алкогольного делірію є невизначеною, хоча відомо про його участь патогенезі цього тяжкого стану. Мета дослідження: виявлення переваг і недоліків седації з додаванням сульфату порівняно зі стандартною седативною терапією. Матеріали та методи. Досліджено 40 пролікованих пацієнтів, які були рандомізовані на 2 групи. Рівень контролювався за Richmond...

Background: Children suffering from cancer always require pain relief and reduce anxiety when undergoing painful procedures. The aim of this study is to compare the effect of pethedine and ketamine administration in cancer-diagnosed children undergoing bone marrow aspiration and biopsy procedures. Subjects and Methods: A randomized, double-blinded, crossover trial was carried out on 57 children...

INTRODUCTION This study aimed to evaluate the pupillary dilatation reflex (PDR) during a tetanic stimulation to predict insufficient analgesia before nociceptive stimulation in the intensive care unit (ICU). METHODS In this prospective non-interventional study in a surgical ICU of a university hospital, PDR was assessed during tetanic stimulation (of 10, 20 or 40 mA) immediately before 40 end...

Aims: Frequent investigation of the patient for determining sedation level is one of the main measures in care of critically ill patient especially after heart surgeries. Riker scale is a valid and reliable tool which has been used in different studies as sedation-agitation scale in patients hospitalized in Intensive Care Unit (ICU). This study had been done with the aim of “investigating the e...

and colleagues, which proposed that delirium measured within 24 hours of admission did not improve the Acute Physiology and Chronic Health Evaluation (APACHE) II in-hospital mortality prediction [1]. Th eir data should be interpreted after considering the study design and statistical limitations. First, the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) measurements include a...

Recent evidence revealed that sedation is related to adverse outcomes including a higher mortality. Despite this fact, patients sometimes require deep sedation for a limited period of time to control, for example, intracranial hypertension. In particular in these cases, weaning from sedation is often challenging due to emerging agitation, stress, and delirium. The submitted research letter repo...

Background: Brain injuries are a major cause of mortality and disability. Sensory stimulation can reduce the complications of brain injuries in the patients.  Objectives: To compare the effect of foot reflexology with tactile stimulation of the hand on level of consciousness and physiological indicators in traumatic brain injury (TBI) patients  Materials & Methods: 60 TBI patients hospitalize...

The aim of this study was to determine the effect of thiopental sodium with that of midazolam-ketamine on relieving agitation after tonsillectomy in children. In a clinical trial, 50 children aged 5-10 years, candidates for tonsillectomy, were randomly divided into two 25-member groups. In the first group, thiopental sodium 5mg/kg/IV, and in the second group combination of midazolam 0.01 mg/kg/...