a bstract background: mechanical ventilation is one of the supporting treatments that are used for different reasons. to reduce patients’ inconvenience caused due to using tracheal tube and ventilator, sedation is routinely used. using scales for the sedation, for example, richmond agitation sedation scale (rass), may reduce dose of sedation and length of mechanical ventilation.   materials and...

BACKGROUND AND OBJECTIVES Sedative and analgesic treatment administered to critically ill patients need to be regularly assessed to ensure that previously stated goals are well achieved as the risk of complications of oversedation is minimized. We revised and prospectively tested the Ramsay Sedation Scale (RSS) for interrater reliability and compared it with the Riker Sedation-Agitation Scale (...

PURPOSE The aim of this study was to compare the correlation between bispectral index (BIS) monitor and four commonly used subjective clinical scales (Ramsay Sedation Scale (RSS), Richmond Agitation Sedation Scale (RASS), Sedation Agitation Scale, Adaptation to Intensive Care Environment scale) in mechanically ventilated patients in intensive care unit (ICU). In addition, comparison of responsi...

OBJECTIVE To implement sedation and delirium monitoring via a process-improvement project in accordance with Society of Critical Care Medicine guidelines and to evaluate the challenges of modifying intensive care unit (ICU) organizational practice styles. DESIGN Prospective observational cohort study. SETTING The medical ICUs at two institutions: the Vanderbilt University Medical Center (VU...

INTRODUCTION Interruption of sedation during weaning from mechanical ventilation often leads to patient agitation because of withdrawal syndrome. We tested the short-term efficacy and tolerance of loxapine in this situation. METHODS Nineteen mechanically ventilated patients with marked agitation after sedation withdrawal were included. Three agitation scales, the Richmond Agitation Sedation S...

OBJECTIVE To assess the feasibility and safety of delivering early goal-directed sedation compared with standard sedation. DESIGN Pilot prospective, multicenter, randomized, controlled trial. SETTING Six ICUs. PATIENTS Critically ill adults mechanically ventilated for greater than 24 hours. INTERVENTIONS Patients randomized to early goal-directed sedation received a dexmedetomidine-base...

background: providing high-quality care in the intensive care units (icus) is a major goal of every medical system. nurses play a crucial role in achieving this goal. one of the most important responsibilities of nurses is sedation and pain control of patients. the present study tried to assess the effect of nurses’ practice of a sedation protocol on sedation and consciousness levels and the do...