BACKGROUND To evaluate whether the location of moist desquamation matches high dose area for breast cancer patients receiving adjuvant radiotherapy (RT) after breast conservative surgery. METHODS One hundred and nine breast cancer patients were enrolled to this study. Their highest skin dose area (the hot spot) was estimated from the treatment planning. We divided the irradiated field into br...

Background: Iran detected its first COVID-19 case in February 2020 in Qom province, which rapidly spread to other cities in the country. Iran, as one of those countries with the highest number of infected people, has officially reported 1812 deaths from a total number of 23049 confirmed infected cases that we used in the analysis. Materials and Methods: Geographic distribution by the map of ca...

We present measurements with the VLBA of the variability in the centroid position of Sgr A* relative to a background quasar at 7mm wavelength. We find an average centroid wander of 71 ± 45μas for time scales between 50 and 100 min and 113± 50μas for timescales between 100 and 200 min, with no secular trend. These are sufficient to begin constraining the viability of the accretion hot-spot model...

LLE Review, Volume 143 125 Introduction In inertial confinement fusion (ICF),1 a shell of cryogenic deuterium (D) and tritium (T) filled with DT gas is imploded with direct laser illumination (direct drive)2 or through an x-ray bath produced inside a laser-irradiated hohlraum (indirect drive).3 Energy from the laser or x ray is absorbed in the plasma near the outer surface of the target, causin...

We present measurements with the VLBA of the variability in the centroid position of Sgr A* relative to a background quasar at 7mm wavelength. We find an average centroid wander of 71±45μas for time scales between 50 and 100 min and 113± 50μas for timescales between 100 and 200 min, with no secular trend. These are sufficient to begin constraining the viability of the hot-spot model for the rad...

MOTIVATION The O-ring theory reveals that the binding hot spot at a protein interface is surrounded by a ring of residues that are energetically less important than the residues in the hot spot. As this ring of residues is served to occlude water molecules from the hot spot, the O-ring theory is also called 'water exclusion' hypothesis. We propose a 'double water exclusion' hypothesis to refine...

The ThyX class of thymidylate synthases was previously characterized by a common ThyX motif, RHRX7S. We report bacterial ThyX sequences having distinctive ThyX motifs, suggesting a more general ThyX motif, R/THRX7-8S. One ThyX sequence has an intein in its ThyX motif that was shown to do protein splicing and a group II intron in its gene, suggesting a hot spot for these self-splicing mobile ele...

PURPOSE Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are similar genetic disorders whose patterns of mutation and disease phenotypes might be expected to show differences among different countries. We analyzed multiplex ligation-dependent probe amplification (MLPA) data in a large number of Korean patients with DMD/BMD. MATERIALS AND METHODS We obtained 130 positive M...

PURPOSE Bone scans showing solitary hot spots in the ribs pose diagnostic problems in patients with proved extraskeletal cancers. The authors wanted to determine the importance of solitary rib lesions and their correlation with other clinical manifestations. MATERIALS AND METHODS The study included 199 patients with solitary rib hot spots on their bone scans. The follow-up radiographic and sc...