Intrahepatic cholestasis of pregnancy (ICP) is characterized by troublesome maternal pruritus, elevated serum bile acids (> or =10 micromol/L) and increased fetal risk. Recently we determined a cutoff level of serum bile acids, > or =40 micromol/L, to be associated with impaired fetal outcome. We have now studied the effects of ursodeoxycholic acid (UDCA) and dexamethasone on pruritus, biochemi...


 One of the most efficient aminoglycoside is amikacin. Yet, it has been linked to unwanted renal toxicity, which resulted in negative alterations various biochemical indicators, particularly those related oxidative stress, kidney function, and inflammation. The goal this research was see how citrus bergamot extract affected hemato-biochemical, inflammatory, stress parameters male rats tri...

Dengue fever is an arboviral infection with the largest incidence worldwide, transmitted by Aedes aegypti. The aim of the study is to study the role of serum transaminases on dengue fever. The serum glutamic oxaloacetic transaminases (SGOT) and serum glutamic pyruvic transaminases (SGPT) were estimated by enzymatic (kinetic) methods for 50 dengue positive cases. Overall, 80% of dengue fever cas...

BACKGROUND AND PURPOSE The availability and promise of effective treatments for neurodegenerative disorders are increasing the importance of early diagnosis. Having molecular and biochemical markers of Alzheimer's disease (AD) would complement clinical approaches, and further the goals of early and accurate diagnosis. Combining multiple biomarkers in evaluations significantly increases the sens...

Objectives: Currently, there are no well-defined biochemical markers for identification of myocardial ischemia in normolipidaemic AMI individuals. Biochemical markers such as CK-MB, cTnI and myoglobin, used in assessing cellular necrosis, are not suitable for assessing myocardial ischemia. The introduction of the Ischemia Modified Albumin (IMA) assay for the first time provides emergency physic...

BACKGROUND There is a high prevalence of diabetes mellitus type-2 (T2DM) and osteoporosis are problems worldwide. In this study, we evaluated the correlation between T2DM and bone turnover in diabetic obese postmenopausal Saudi women. SUBJECTS AND METHODS The present study included total of 65 T2-DM obese postmenopausal Saudi women, (36 uncontrolled, 29 controlled). The following serum bioche...