The synthesis of stereoisomers of acuminatolide is rare and requires complex and time-consuming multistep procedures. Asarinin (1) and sesamin (2), two diasteromeric tetrahydrofurofuran lignans, are efficiently mono-dearylated by methyltrioxorhenium (MTO, I) and hydrogen peroxide (H2O2) or urea hydrogen peroxide adduct (UHP) as primary oxidant to give (-)-(7R,8'R,8R)-acuminatolide (3A) and (+)-...

Episesamin is an isomer of sesamin, resulting from the refining process of non-roasted sesame seed oil. Episesamin has two methylendioxyphenyl groups on exo and endo faces of the bicyclic skeleton. The side methylendioxyphenyl group was metabolized by cytochrome-P450. Seven metabolites of episesamin were found in rat bile after treatment with glucuronidase/arylsulfatase and were identified usin...

The major issue of the current era is an unbalanced and poor diet like unhealthy fast foods, main cause various diseases. Most nutraceutical pharma industries formulating medicines from artificial sources are expensive have several side effects. However, scientists making efforts to find out natural for betterment human health treatment Simultaneously, worldwide preferences shifted resources un...

A phytochemical study of Tecoma genus (Bignoniaceae) was accomplished by antitumor activity ethanolic extracts. Species this are composed small shrubs often used as ornamental plants. The stans species is in folk medicine for different purposes. Recent work shows vitro anticancer against human breast cancer. extracts from leaves and trunks casneifolia, T. garrocha, var. angustata were tested vi...