background: despite major progress in our general knowledge related to the application of adult stem cells, finding alternative sources for bone marrow mesenchymal stem cells (mscs) has remained to be challenged. in this study successful isolation, multilineage differentiation, and proliferation potentials of sheep mscs derived from bone marrow, adipose tissue, and liver were widely investigate...

background: repeated implantation failure (rif) is one of the most intricate obstacles in assisted reproduction. the cytokine and chemokine composition of uterine cavity seem to play important roles in the implantation process. objective: to compare the cytokine profile in the endometrium of normal fertile women and those with repeated implantation failure. methods: after enzymatic digestion of...

gastrointestinal stromal tumors (gist) are the most common mesenchy­mal tumors of the gastrointestinal tract. the biological pattern of these tumors ranges from benign-appearing small lesions to malignant sarcomas. only 3%-5% of gists are found in the duodenum. a duodenal gist is a rare source of upper gastrointestinal bleeding. a remarkable percentage of duodenal gists are localized in the thi...

background gastrointestinal stromal tumors (gists) are potentially malignant tumors; however their behavior and response to treatment is dependent on the type of mutation and immunohistochemical expression of antigens. it is recommended to perform routine molecular and immunohistochemical tests in kit and platelet derived growth factor receptor alpha (pdgfra) molecules for making decision regar...

 Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra Sonography, and a rise of total and free serum testosterone. An ovarian source of androgen was suspected and a surgery performed. A diagnosis ...

endometrial stromal sarcoma represents a very rare pathological entity occurring as a malignant disease in women genital sphere, frequently in the age group of 40-50 years. low grade endometrial stromal sarcoma (lgess) is a rare uterine sarcoma constituting 0.2% of all the uterine malignancies with a good prognosis despite a tendency to recur. we report a case of 42 years old woman presented wi...

BACKGROUND Our previous studies demonstrated the expression of procollagen11A1 in fibroblasts of pancreatic cancer desmoplasia and the lack of expression in fibroblasts of pancreatitis by means of the polyclonal antibody (anti-proCOL11A1 pAb) we generated. In a similar way, we decided to compare the expression of procollagen11A1 in fibroblasts of infiltrating ductal carcinoma of the breast and ...

the gastrointestinal stromal tumor (gist) is a rare mesenchymal tumor of gastrointestinal (gi) tract. this tumor has tendency to liver metastasis and peritoneal recurrence, however; the primarily lymph node involvement or metastasis is rare. here we reported a 17-years-old girl with multifocal gastric gist and multiple lymph node involvement at presentation and recurrence in celiac lymph nodes....