BACKGROUND The objective of the present study was to investigate sublingual microvascular blood flow and microcirculatory haemoglobin oxygen saturation (Smc(O(2))) during cardiopulmonary bypass (CPB) using constant systemic blood flow but different perfusion pressures achieved by phenylephrine administration. METHODS Fifteen patients undergoing coronary artery bypass grafting were enrolled in...

BACKGROUND Compliance with prescribed treatment is essential for reducing costs of health care and improving efficacy of treatment in patients with allergic rhinitis. OBJECTIVE To evaluate the extent of compliance and identify predictive factors and risk profiles for patient noncompliance with the therapeutic regiments of sublingual immunotherapy and H1-antihistamines. METHODS In this retro...

BACKGROUND Sublingual administration of allergens is a safe and effective alternative to subcutaneous immunotherapy in patients with respiratory allergies. A drawback to this therapeutic approach is the relatively long and complex management of the induction phase. AIM OF THE STUDY To determine whether different induction regimens affect the outcome of sublingual immunotherapy. METHODS AND ...

BACKGROUND Allergy immunotherapy is an effective way to manage the allergic patient and may be administered either through the subcutaneous route (SCIT) or the sublingual route (SLIT). Both have been proven efficacious; however, SLIT is currently not covered by insurance companies and is an out-of-pocket expense. The goal of the current study is to compare the costs of SCIT to SLIT. METHODS F...

OBJECTIVES The purpose of this study was to compare the effect of different antihypertensive agents, calcium antagonists, angiotensin-converting enzyme (ACE) inhibitors, beta-blockers and diuretic agents on endothelial function. BACKGROUND Endothelial dysfunction is a component of essential hypertension, and various antihypertensive drugs may be able to restore normal function. METHODS Fore...

background: to assess the endothelial function via noninvasive method, in pregnant women with preeclampsia compared to normotensive pregnant women. materials and methods: brachial artery diameter was measured via ultrasound, in 28 women with preeclampcia in case group and normotensive pregnant women in control group, at rest, after inflation of sphygmomanometer cuff up to 250-300 mmhg, immediat...

BACKGROUND Sublingual allergen immunotherapy is an effective treatment against allergic respiratory disease. Many studies have shown the safety of this type of therapy, although the factors that might affect the tolerability of high-dose sublingual immunotherapy have not been well established. The aim of this study was to determine the factors that affect the tolerability of sublingual allergen...

background: postoperative pain is a common side effect following surgery that can significantly reduce surgical quality and patient’s satisfaction. treatment options are morphine and buprenorphine. we aimed to compare the efficacy of a single dose of intravenous morphine with sublingual buprenorphine in postoperative pain control following closed reduction surgery. methods: this triple blind cl...

INTRODUCTION The hypertensive emergencies in haemodialysis require immediate therapy, usually by parenteral drug administration; however, sublingual medications may have a potential in this special condition. METHODS A prospective, non randomized, case control study was carried out to know the effectiveness and the safety of a single dose of 5mg Nifedipine (sublingual) in this subset of patie...