نتایج جستجو برای: tau convolution
تعداد نتایج: 37435 فیلتر نتایج به سال:
The tau subunit of Escherichia coli DNA polymerase III holoenzyme interacts with the alpha subunit through its C-terminal Domain V, tau(C)16. We show that the extreme C-terminal region of tau(C)16 constitutes the site of interaction with alpha. The tau(C)16 domain, but not a derivative of it with a C-terminal deletion of seven residues (tau(C)16Delta7), forms an isolable complex with alpha. Sur...
Tau, a microtubule associated protein, aggregates into intracellular paired helical filaments (PHFs) by an unknown mechanism in Alzheimer's disease (AD) and other tauopathies. A contributing factor may be a failure to metabolize free cytosolic tau within the neuron. The buildup of tau may then drive the aggregation process through mass action. Therefore, proteases that normally degrade tau are ...
Hyperphosphorylation and deposition of tau into neurofibrillary tangles is a hallmark of Alzheimer disease (AD). Alternative splicing of tau exon 10 generates tau isoforms containing three or four microtubule binding repeats (3R-tau and 4R-tau), which are equally expressed in adult human brain. Dysregulation of exon 10 causes neurofibrillary degeneration. Here, we report that cyclic AMP-depende...
We denote each fully-connected layer fc(d) by its output dimension d, and volumetric convolution layer by conv3D(k, c, s) representing kernel size of k, strides of s across three spatial axes, and c channels. 2D convolutional layer is represented as conv2D(k, c, s). and the volumetric transpose convolution layer by deconv3D(k, c, s). Encoder and Generator for Aligned Shapes The variational alig...
در این تحقیق اثرات باسیلوس های پروبیوتیکی بر روی انرژی مصرف شده و دفع آمونیاک و اوره در لارو ماهیان قزل آلا با بکارگیری مخلوط پنج گونه از باسیلوس های پروبیوتیکی از طریق مکمل سازی جیره به مدت 60 روز بررسی شد. لاروهای ماهی قزل آلا (با وزن متوسط 32±463 میلی گرم) با جیره (تیمار Tau-1) حاوی 106*1 CFL/ml، (تیمار Tau-2) حاوی 107*1 CFL/ml و (تیمار Tau-3) حاوی 108*1 CFL/ml در هر 100 گرم غذا مکمل سازی شد...
Abnormal accumulation of the microtubule-interacting protein tau is associated with neurodegenerative diseases including Alzheimer's disease (AD). β-amyloid (Aβ) lies upstream of abnormal tau behavior, including detachment from microtubules, phosphorylation at several disease-specific sites, and self-aggregation into toxic tau species in AD brains. To prevent the cascade of events leading to ne...
Abstract. R-limited functions are multivariate generalization of band-limited functions whose Fourier transforms are supported within a compact region R ⊂ Rn. In this work, we generalize sampling and interpolation theorems for band-limited functions to R-limited functions. More precisely, we investigated the following question: “For a function compactly supported within a region similar to R, d...
From electron-positron collision data collected with the CLEO detector operating at Cornell Electron Storage Ring near sqrt[s]=10.6 GeV, improved measurements of the branching fractions for tau decays into three explicitly identified hadrons and a neutrino are presented as B(tau(-)-->pi(-)pi(+)pi(-)nu(tau))=(9.13+/-0.05+/-0.46)%, B(tau(-)-->K-pi(+)pi(-)nu(tau))=(3.84+/-0.14+/-0.38) x 10(-3), B(...
Recent studies have demonstrated that human tau can be secreted by neurons and non-neuronal cells, an event linked to the propagation of tau pathology in the brain. In the present study, we confirmed that under physiological conditions, one tau-positive band was detected in the culture medium with an anti-tau antibody recognizing total tau and the Tau-1 antibody directed against unphosphorylate...
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