Gastric Ulceration in the Adult Gastric ulceration syndrome (GUS), a complicated and multi-factorial problem, is a common disorder of the stomach of mature horses. Horses that are turned out to pasture and are not involved in work have normal stomachs as do most horses used for light work or pleasure (Murray 1994). In recent years the widespread nature of this disorder has gained increased reco...

An experimental model was used which includes intragastric instillation of 80 mM HCl and 0.6 ml bile/kg followed by intravenous infusion of live E coli in cats for up to three hours. This procedure regularly induces gastric mucosal ulcerations. Mucosal blood flow was measured by microspheres before, early, and late in sepsis. Total gastric blood flow was recorded electromagnetically. Mucosal re...

BACKGROUND Behçet's syndrome (BS) is a multisystem immune-related disease of unknown etiology. Recurrent aphthous stomatitis (RAS) is characterized by the presence of idiopathic oral ulceration without extraoral manifestation. The interplay between the oral microbial communities and the immune response could play an important role in the etiology and pathogenesis of both BS and RAS. OBJECTIVE...

Various degrees of esophageal injury have been described after radiofrequency ablation performed for treatment of atrial fibrillation. The main mechanism of injury is thermal and may lead to a range of esophageal mucosal changes, some clinically insignificant, however when deep ulceration occurs, this may be further complicated by perforation and mediastinitis, a rare but life threatening seque...

A 73 year old female presented with progressive hypoproteinaemic oedema which was resistant to treatment. The cause was not established until post-mortem, when it was found that she had angiotropic large cell lymphoma involving the vessels of the large intestine with mucosal ulceration. To our knowledge, this is the first report of angiotropic large cell lymphoma, which usually presents with ne...

Alimentary tract duplications are uncommon congenital anomalies. Although most are symptomatic by the age of 2 years, some remain asymptomatic until adulthood. In one third of all cases, heterotopic gastric mucosa lines the wall of dupli­ cation, and may cause peptic ulceration, gastrointestinal bleed­ ing, fistulization or perforation. We report in this paper, a case of jejunoileal duplication...

Keratoconjunctivitis sicca, conjunctival scarring, fibrosis, metaplasia, and shrinkage developed in 27 patients as an adverse reaction to practolol. Rashes, nasal and mucosal ulceration, fibrous or plastic peritonitis, pleurisy, cochlear damage, and secretory otitis media also occurred in some cases. Three patients suffered profound visual loss though most retained good vision. Symptoms and sig...

This contribution reviews briefly the history of the discovery and characterization of peptic activity; secretory models and current concepts regarding the regulation of pepsinogen secretion; and evidence that pepsin is a necessary co-factor for gastroduodenal mucosal injury. Several animal studies indicate that peptic activity is required for acid- and nonsteroidal anti-inflammatory drug-induc...

A case of Kaposi' s sarcoma involving the small bowel two years after receiving a re nal transplant is described. Immunosuppression had been achieved using cyclosporine A and prednisolone. Lesions extended from the duodenum to the ileum; radiologically, they were demonstrated on small bowel follow-through study and computed tomography as multip!e small nodu!ar intra!umina! masses with or withou...