Series of novel dichromophoric cyanine dyes based on 2-aminobenzothiazoles and 3-amino-1,2,4 -triazole have been synthesized in high yields. All the dyes have been classified as disperse dyes. Besides their electronic spectroscopic properties, high dye-uptakes on polyester, excellent fastness properties, highly extinction coefficients, and broad solvatochromic effects have been observed in thes...

Growth of Chlorella vulgaris and Prototheca zopfii is inhibited by treatment with 3-amino-1,2,4-triazole. Growth of these 2 algae in the presence of amino triazole is accompanied by the accumulation in the culture media of the dephosphorylated histidine precursor, imidazoleglycerol. The addition of histidine to the culture media in the presence of amino triazole restored the normal growth rates...

Growth of Chlorella vulgaris and Prototheca zopfii is inhibited by treatment with 3-amino-1,2,4-triazole. Growth of these 2 algae in the presence of amino triazole is accompanied by the accumulation in the culture media of the dephosphorylated histidine precursor, imidazoleglycerol. The addition of histidine to the culture media in the presence of amino triazole restored the normal growth rates...

In the mol-ecule of the title compound, C(10)H(9)N(3)O, the triazole and phenyl rings are nearly perpendicular to each other, with a dihedral angle of 88.72 (4)°. In the crystal structure, inter-molecular C-H⋯O and C-H⋯N hydrogen bonds link the mol-ecules. There are C-H⋯π contacts between the 1,2,4-triazole rings, and between the phenyl and 1,2,4-triazole rings, and there is a weak π-π contact ...

The use of 4-amino-5-benzyl-4H-[1,2,4]triazole-3-thiol (1) as a precursor to synthesize some new biologically active heterocycles has been found to be effective. Condensation of 1 with appropriate aldehydes gave the new Schiff bases 2a, b, which either by cyclization with thioglycolic acid gave 3a, b, or by Mannich reaction using morpholine gave 4a, b. Reaction of 1 with different halogen compo...

Abstract Resolving the regioselectivity of N-position on nitrogen-rich heterocycles is an important task in synthesis high energy density materials (HEDMs). In this work we developed a simple two-step route to introduce 1,2,4-triazole into 4-nitro-1,2,3-triazole N2-position, which shows excellent regioselectivity. The target compound 4-nitro-2-(1 H -1,2,4-triazol-3-yl)-1,2,3-triazole (3) was ch...

We have synthesized and studied the biological and biophysical properties of triazole-linked ribo and xylo locked nucleic acid (LNA). The combination of LNA with the Isobe triazole linkage gave high binding affinity when incorporated at the 3' or 5' termini of oligonucleotides, but low binding affinity at internal positions. Antisense oligonucleotides (ASOs) and siRNAs containing triazole dimer...

In the title sydnone compound, C(20)H(18)ClN(7)O(4)S, the oxadiazole, triazole, chloro-substituted and meth-oxy-substituted phenyl rings are essentially planar, with maximum deviations of 0.007 (3), 0.009 (2), 0.017 (2) and 0.002 (3) Å, respectively. The dihedral angles between the chloro-substituted phenyl ring and the triazole ring, the triazole ring and the oxadiazole ring, and the oxadiazol...