purpose: to report the efficacy of a single intravitreal injection of bevacizumab (ivb) alone or in com-bination with intravitreal triamcinolone acetonide (ivt) versus macular laser photocoagulation (mpc) as primary treatment for diabetic macular edema (dme). methods: this randomized three-arm clinical trial included 103 eyes of 97 patients with clinically significant dme and no previous treatm...

PURPOSE The purpose was to report the structural, visual, and refractive outcomes of infants treated for retinopathy of prematurity (ROP) with laser and to identify the risk factors for unfavorable outcomes. MATERIALS AND METHODS The charts of infants with severe ROP treated by diode laser in a tertiary center during the period April 1999 to November 2003 were reviewed. Treated infants were f...

purpose : to assess the results of intracorneal ring (icr) segments for treatment of patients with pellucid marginal degeneration (pmd) methods : in this prospective interventional case series study, eight eyes of 5 patients with pmd who were contact lens intolerant received one or two intacs (intacs, addition technology) segments. preoperative and postoperative evaluations included slit-lamp e...

purpose: to compare intravitreal bevacizumab (ivb) with intravitreal triamcinolone acetonide (ivt) for treatment of refractory uveitic cystoid macular edema (cme). methods: in this randomized clinical trial, 31 eyes with uveitic cme were allocated into 2 groups: the ivb group, received one to three injections of 1.25 mg bevacizumab (15 eyes); the ivt group received one to three injections of 2m...

OBJECTIVE To assess the course of change of visual function outcome variables in 5 patients with gyrate atrophy before a gene replacement therapy clinical trial. METHODS The outcome variables selected were visual field sensitivity and electroretinogram amplitude. The course of change of these outcome variables was determined by calculation of their half-lives. RESULTS In the 4 to 6 years du...

Aim: To offer a critique of current methods of defining amblyopia treatment outcome and to examine alternative approaches. Method: Literature appraisal and descriptive case presentations. Results: Currently, the outcome of amblyopia treatment is expressed as the number of acuity chart lines gained or, alternatively, achievement of an arbitrarily adopted level of visual acuity. As binocular visi...

OBJECTIVE To evaluate how often visual acuity outcomes are reported in the ophthalmological literature as best or final outcomes, despite potential bias with this type of analysis, as compared with interval outcomes, when a specific condition may continue to cause gain or loss of visual acuity beyond the time that the best or final outcome is determined. METHODS Each article published in the ...

AIM To offer a critique of current methods of defining amblyopia treatment outcome and to examine alternative approaches. METHOD Literature appraisal and descriptive case presentations. RESULTS Currently, the outcome of amblyopia treatment is expressed as the number of acuity chart lines gained or, alternatively, achievement of an arbitrarily adopted level of visual acuity. As binocular vis...

Background: Pituitary adenoma, which accounts for 17.4% of all brain tumors, is the third most frequently diagnosed brain tumor, following intracranial glioma and meningioma. The visual disturbance in pituitary adenoma ranged from blurring of vision with or without headache to total loss of vision. In patients with visual field defects, bitemporal hemianopia was the commonest visual field defec...