Boron neutron capture therapy (BNCT), a binary treatment modality that can potentially irradiate tumor tissue within cellular dimensions, is critically dependent on the preferential delivery of '"IS to individual neoplastic cells. In this study, ion microscopy was used to quantitatively evaluate the selectivity of p-boronophenylalanine-fructose (BPA-F) in the rat 9L gliosarcoma brain tumor mode...

INTRODUCTION Demographic analysis shows the ageing of the global population and the consequent increase in the age of hospitalized subjects and of patients starting dialysis. Hence, interest in the feasibility, safety, and usefulness of renal biopsy in elderly patients is growing. We examined the data of 131 patients over the age of 75 who underwent renal biopsy. We analyzed the safety of the p...

Hilbert Space of a Single Fermionic Mode A single bosonic mode is equivalent to a harmonic oscillator; the relation [â, â†] = 1 gives rise to an infinite-dimensional Hilbert space spanning states |n〉 for n = 0, 1, 2, 3, . . . ,∞. A single fermionic mode is different — its Hilbert space spans just two states, |0〉 and |1〉. In accordance with the Fermi statistics, multiple quanta in the same mode ...

Administration of phénobarbital (7.5 mg/100 gm) to rats for 2 days increased the mean concentration of hepatic cytochrome P-450 from 2.1 ±0.5 units to 5.1 ±0.8 units, and increased the mean hepatic weight from 4.4 ±0.3 percent of body weight to 5.0 ± 0.4 percent. Phénobarbital induction of cytochrome P-450 and phénobarbitalstimulation of hepatic enlargement were blocked by injection of n...

Cocoa butter was crystallized statically from the melt to various temperatures in the range of -20 to 26 °C and annealed for up to 45 days. During this period, the polymorphism of the solid state was monitored using differential scanning calorimetry and powder X-ray diffraction. Moreover, the microstructure of the materials was imaged using polarized light microscopy. Below -15 °C, a mixture of...

The in vivo fate of various “In-labeled polypeptides has been the subject of many investigations. Intracellular metabolism has been StUdied through the use of “In-labeled glycoproteins that are concentrated in the lysosome by receptor-mediated endocytosis. These studies have Indicated that the main lysosomal metabolite is “In-chelate-e-lysine, both in vitro and in vivo (Y. Arano et aL, J....

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