Rosmarinic acid (RA) is a multifunctional caffeic acid ester present in sweet basil (Ocimum basilicum L.). Untransformed normal roots of O. basilicum harbored the maximum titers (0.98% g fresh weight basis) of RA compared to leaves and shoots. Hairy root cultures of O. basilicum transformed with Agrobacterium rhizogenes (ATCC-15834) showed three-fold increases in growth and RA production compar...

The antifungal activity and the chemical composition of essential oils (EOs) from some Mediterranean autochthonous plants were investigated against Malassezia pachydermatis, a fastidious opportunistic yeast usually involved in canine external otitis. Minimum inhibitory concentrations (MICs) of Anthemis nobilis, Citrus limon, Citrus paradisi, Illicium verum, Lavandula hybrida, Mentha piperita, O...

The anti-trypanosomal effects of aqueous extract of the leaf of Ocimum gratissimum were evaluated in both in-vitro and in-vivo studies. The anti-trypanosomal activity of the extract against Trypanosoma brucei was investigated in-vitro. The survival and motility of the trypanosomes were completely inhibited within two hours of incubation in various concentrations of the extract. Parasite surviva...

Ocimum basilicum, popularly known as Basil, is a Lamiaceae family species widely known to treat different diseases. This species has as its main compound the monoterpene linalool. This study aimed to determine the antibacterial activity of O.basilicum essential oil and linalool against S. aureus and P. aeruginosa strains, as well as times to bacterial death facing each substance. The extraction...

Correspondence to: Emeka E.J. Iweala, Department of Biological Sciences, Biochemistry and Molecular Biology Unit, Covenant University, P.M.B 1023, Ota, Ogun State, Nigeria. Email: [email protected] Full Paper Preliminary qualitative screening for cancer chemopreventive agents in Telfairia occidentalis Hook.f., Gnetum africanum Welw., Gongronema latifolium Benth. and Ocimum gratissimum...