AIM To determine the overall and comparative risk of procedure related perforation of balloon assisted enteroscopy (BAE) in Crohn's disease (CD). METHODS Systematic review (PROSPERO #CRD42015016381) of studies reporting on CD patients undergoing BAE. Seventy-three studies reporting on 1812 patients undergoing 2340 BAEs were included. Primary outcome of interest was the overall and comparative...

Obscure gastrointestinal bleeding (OGIB) accounts for 5% of all gastrointestinal (GI) bleeding cases and is often caused by small bowel lesions. Capsule endoscopy (CE), which allows non-invasive visualization of the small bowel mucosa, has revolutionized the evaluation of OGIB. CE is preferred by both patients and physicians mainly because of its non-invasiveness, and is widely used as the firs...

background: Endoscopic access to the biliary system can be difficult in patients with surgically altered anatomy, such as a roux-en-Y reconstruction. double balloon enteroscopy (dbE) is a relatively new procedure that enables access to the small bowel. dbE has recently been advocated as a method for endoscopic retrograde cholangiopancreaticography (ErCP) in patients with surgical reconstruction...

Objective Balloon-assisted endoscopy enables access to and treatment of strictures in the small intestine using endoscopic balloon dilation (EBD); however, the long-term outcomes of EBD have not been sufficiently evaluated. This study evaluated the long-term outcomes of EBD in Crohn's disease to identify the risk factors associated with the need for subsequent surgical intervention. Methods We ...

A 63-year-old man with a history of surgery for thoracic aortic dissection was transferred to our hospital with obscure gastrointestinal bleeding (OGIB) and bloody stools. Laboratory examination revealed the following results: hemoglobin, 9.9g/dL; platelets, 94000/μL; creatinine, 1.29mg/dL. Video capsule endoscopy following anterograde and retrograde double-balloon enteroscopy (DBE) could not i...

In this study, a dabigatran etexilate edisylate (DBE) was prepared by the reaction crystallization of (DBG) and edisilic acid. According to single crystal X-ray diffraction (SXRD), it revealed that two DGB were combined with one associated water for DBE monohydrate. Additionally, hot stage microscopy showed monohydrate transformed amorphous solid then finally shifted anhydrate in solid-state. U...

BACKGROUND Double balloon enteroscopy is a new technique that enables deep intubation of the endoscope into the small bowel lumen. Through a channel in the endoscope, invasive procedures such as biopsy, polypectomy and hemostasis can be performed, avoiding the need for surgery. OBJECTIVES To prospectively analyze our results of the first 124 DBEs performed since February 2007. METHODS The s...

This paper addresses the role of trust and regulation where small and medium-sized enterprises (SMEs) in the European Union make use of e-business in a digital business ecosystem (DBE). We argue that in order for digital business to develop among entrepreneurs in the EU and within different industry sectors and geographical locations, trust and regulation are of critical importance. The paper a...

The varying-coe¢ cient partially linear model (VCPLM) is a mixture of the varying-coe¢ cient model (VCM) and partially linear model (PLM). It improves over both of them in terms of ‡exibility. It allows the coe¢ cient of the nonlinear component to vary according to some additional variables so that the model is ‡exible enough to express complicated real-world phenomena. In addition VCPLM can al...