BACKGROUND Urinary tract infections (UTIs) caused by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae have become clinical problems because of limited therapeutic options. The role of fosfomycin in the era of growing bacteria resistance has been widely discussed recently. In this study, we aimed to know the local antimicrobial susceptibilities, fosfomyci...

BACKGROUND AND PURPOSE Infections due to extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae (ESBL-EC and ESBL-KP) have become an important clinical problem. Local knowledge of antimicrobial susceptibilities of these organisms is important for implementation of effective hospital anti-infective policies. METHODS We analyzed the activities of various an...

The present study investigated the microbial etiologies and clinical impact of extended‑spectrum β‑lactamase (ESBL)‑producing bacteria according to urine blood cultures from patients with acute pyelonephritis (APN). Data all (age >15 years) who had been hospitalized at a single hospital APN were collected between January, 2010 December, 2018. Overall, 882 included. Patients divided into an E...

We investigated the gastrointestinal colonization rate and antibiotic resistance patterns of Extended-Spectrum Beta-Lactamase (ESBL)- producing Escherichia coli and Klebsiella pneumoniae in hospitalized patients admitted at Ethiopia's largest tertiary hospital. Fecal samples/swabs from 267 patients were cultured on chrome agar. ESBL. Bacterial species identification, verification of ESBL produc...

OBJECTIVE We hypothesized that admission screening for extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) reduces the incidence of hospital-acquired ESBL-E clinical isolates. DESIGN Retrospective cohort study. SETTING 12 hospitals (6 screening and 6 non-screening) in Toronto, Canada. PATIENTS All adult inpatients with an ESBL-E positive culture collected from 2005-2009. ...

کاهش هزینه‏‌های مرتبط با موجودی از مهم‌ترین استراتژی‌‏های هر بنگاه اقتصادی برای بقا و سوددهی در شرایط رقابتی امروزی است. این راستا مدل‏‌های کلاسیک هزینه‏‌ها مطرح شده‌اند؛ اما کنار مزایای فراوان دارای فرضیه‌های محدودکننده‌ای هستند. پژوهش، یک زنجیره سه­‌سطحی لجستیکی شامل تولیدکننده، توزیع‌‏کننده خرده‏‌فروش نظر گرفته می‏‌شود مسئله بهینه‌سازی مدل توزیع‌کننده موردبررسی قرار می‏‌گیرد. موردنظر، توزیع‏...

AIM To compare the performance of a new chromogenic agar medium CHROMagar ESBL (KC-ESBL) to chromID ESBL (SB-ESBL) for the detection and presumptive identification of extended-spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae directly from clinical specimens. METHODS AND RESULTS A total of 256 specimens were screened for ESBL producers. Also, the genotypes of the ESBLs and plasmid-medi...