BACKGROUND Endothelial progenitor cells (EPCs) have been identified in adult human peripheral blood. Because circulating EPCs should originate from bone marrow (BM), we examined whether BM mononuclear cells (BM-MNCs) can give rise to functional EPCs and whether transplantation of autologous BM-MNCs might augment angiogenesis and collateral vessel formation in a rabbit model of hindlimb ischemia...

BACKGROUND/AIMS Therapies involving bone-marrow-derived mesenchymal stem cells (BM-MSCs) have considerable potential in the management of hepatic disease. BM-MSCs have been investigated in regenerative medicine due to their ability to secrete various growth factors and cytokines that regress hepatic fibrosis and enhance hepatocyte functionality. The aim of this study was to determine the antifi...

BACKGROUND Brain metastases (BM) and leptomeningeal disease (LMD) are uncommon in epithelial ovarian cancer (EOC). We investigate the outcomes of modern radiation therapy (RT) as a primary treatment modality in patients with EOC BM and LMD. METHODS We evaluated 60 patients with EOC treated at our institution from 1996 to 2010 who developed BM. All information was obtained from chart review. ...

Large gaps in basement membrane (BM) occur during organ remodelling and cancer cell invasion. Whether dividing cells, which temporarily reduce their attachment to BM, influence these breaches is unknown. Here we analyse uterine-vulval attachment during development across 21 species of rhabditid nematodes and find that the BM gap that forms between these organs is always bounded by a non-dividin...

And (C)always (Am)look on the (Dm)bright (G7)side of (C)life. (Am)(Dm)(G7) (C)Always (Am)look on the (Dm)right (G7)side of (C)life. (Am)(Dm)(G7) (Come on guys, cheer up!) (D)Always (Bm)look on the (Em)bright (A7)side of (D)life. (Bm)(Em)(A7) (D)Always (Bm)look on the (Em)bright (A7)side of (D)life. (Bm)(Em)(A7) (Worse things happen at sea, you know.) (D)Always (Bm)look on the (Em)bright (A7)sid...

Objective(s):The limited homing potential of bone-marrow-derived mesenchymal stem cells (BM-MSC) is the key obstacle in MSC-based therapy. It is believed that chemokines and chemokine receptor interactions play key roles in cellular processes associated with migration. Meanwhile, MSCs express a low level of distinct chemokine receptors and they even lose these receptors on their surface after a...

The aim of the present research was to analyze the body composition (BC) and the differences in BC among different playing position in professional basketball, handball and futsal players. BC was assessed in 70 professional indoor team sport players. Players were divided in 4 groups depending on the playing position: group 1, point guard, center/wings and defense; group 2, shooting guard/small ...