An efficient one pot multi component synthesis of 1, 4-Polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction using lanthanum chloride heptahydrate (LaCl3.7H2O) from an aromatic aldehyde, ethyl acetoacetate, dimedone and ammonium acetate as a nitrogen precursor in ethanol at room temperature is described. In the present work we report lanthanum chloride heptahydrate remarkably n...

Antibacterial activity of the aerial extracts from Xanthium brasilicum prepared in methanol, diethyl ether, petroleum benzene and an equal mixture of the three solvents were studied against bacterial laboratory standards and clinical isolates using the disk diffusion method. The best antibacterial results were obtained when methanol or the solvent mixture was used. The crude extract with the hi...

In the present work, a series of new 5-substituted-3-(4-arylimino)-1-[5-mercapto(1,3,4-oxadiazolyl)]-methyl-indol-2-one (4a-g) have been synthesized by heterocyclization of 5-substituted-3-(4-arylimino)-2-oxo-1-indole acetylhyrazide (3a-g) on treatment with CS2 in ethanolic KOH. The compound 4a was characterized by its elemental analysis, IR, 1HNMR and Mass Spectroscopy. The synthesized compoun...

In this manuscript, a new series of 1,2,4-triazole-3-ones containing imin function was synthesized from 5-(4-bromobenzyl)-4-amino-2H-1,2,4-triazol-3(4H)-one and aromatic aldehyde by using microwave irradiation technique via schiff base reaction. Firstly, ethyl imido-p-bromophenylacetate hydrochloride (2) according to the pinner method in literature. Then, compound 2 reacted with carbazate p-bro...

Peptides have shown Promising effect as pharmaceutics with the potential to treat a widevariety of diseases. Peptides are mostly synthesized by biological technology or chemicalmethods. Solution phasepeptide synthesis (SPS) and solid phase peptide synthesis (SPPS) aretwo major chemical techniques for peptidesproduction.In this research, the synthesis ofdipeptde(β-alanine-L-histidine)wasexamined...

Two flavonids: 5-hydroxy-6,7,4 ́-trimethoxy flavone (salvigenin), 5-hydroxy-7,4 ́-dimethoxy flavone(thitonine) and a labdane type diterpenoid: 8,13-epoxy-14 labdene (manoyl oxide) isolated from the solventextract of the aerial part of Salvia reuterana Boiss.The proposed structure were stablished by 1HNMR,13CNMR, 2DNMR( C-H-Cosy, HMQC),DEPT and Mass spectroscopy and confirmed in accordance withbib...