The activity of alginic acid as a cytotoxic agent was improved by structure modification using 4-aminophenol (4-AP) through condensation and polymerization processes. Then, silver nanoparticles were employed doping to further enhance the modified polymer. prepared materials characterized FT-IR, 1HNMR, UV spectroscopy, X-ray diffraction, electron microscopy, thermal behavior all synthesized inte...

The basolateral amygdala (BLA) has substantial effects on the neuronal transmission and synaptic plasticity processes through the dentate gyrus. Orexin neuropeptides play different roles in the sleep/wakefulness cycle, feeding, learning, and memory. The present study was conducted to investigate the function of the orexin receptors of the BLA in the hippocampal local interneuron circuits. For t...

Nomenclature for the chemerin receptors is presented as recommended by NC-IUPHAR [15, 44]). The chemoattractant protein and adipokine, chemerin, has been shown to be endogenous ligand both family receptors. Chemerin1 was founding member, when GPR1 de-orphanised it re-named Chermerin2 [44]. also activated lipid-derived, anti-inflammatory resolvin E1 (RvE1), which formed via sequential metabolism...

43 individuals (medical workers) were examined, 15 of them suffered from COVID-19;7 persons had negative PCR tests, however, there signs a respiratory infection in the anamnesis;21 participants denied having COVID-19 and any infections past year. The serum level neutralizing IgG to S-Trimer Protein SARS-Cov-2 was determined. number antigen-recognizing receptors B-lymphocytes represented by memb...

introduction: activation of n-methyl-d-aspartate (nmda) glutamate receptors in the nucleus accumbens is a component of drug-induced reward mechanism. in addition, nmda receptors play a major role in brain reward system and activation of these receptors can change firing pattern of dopamine neurons. blockade of glutamatergic neurotransmission reduces the expression of conditioned place preferenc...

Background and Objectives: Cyclooxygenese-2 (COX-2) expression in breast cancer and its correlation with tumor prognosis is unclear. We investigated the incidence of COX-2 expression in patients and assessed interactions between COX-2 and clinical features of cancer and expression of HER2/neu, estrogen receptor (ER), and progesterone receptor (PR). Methods: COX-2 expression was investigated by...