background and objective: breast cancer is the commonest cancer of indian women. estrogen and progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

intraperitoneal (ip) injection of bupropion (3,6, amine (4,16 mg kg•&apos;) induced dose-dependent climbing in mice. the climbing response induced by both drugs were decreased in animals pretreated either with the 0-1 antagonist sch 233<)0 or the 0-2 antagonist sulpiride. the α-adrenoceptor blocker phenoxybenzamine decreased the climbing induced by both bupropion and amphetamine, but the β-adre...

conclusions our findings showed that the genotype tt rs53576 oxtr, as well as t allele had significant differences in our population and play a protective role. therefore, it is suggested to place more interest on these oxtr in large populations and different ethnic groups. results the logistic regression analysis suggested no significant associations of oxtr single nucleotide polymorphism (snp...

background and objectives: breast cancer is the most common malignancy among women in the world. the aim of this study was to assess estrogen receptor (er), progesterone receptor (pr) and her-2/neu of infiltrating ductal carcinoma (idc) with tumor size, histologic grade, lymph node metastasis and age. methods: this study was carried out on 300 tissue blocks ofpatients with idc who underwent mas...

Background and Objective: Breast cancer is the commonest cancer of Indian women. Estrogen and Progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. Although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

results in patients with high breast densities, malignant cases (61.2%) were significantly more in comparison to patients with low breast densities (37.3%) (p= 0.007, or=2.66 95% ci=1.29-5.49). after adjusting for age, density was associated with malignancy in age groups <46 years (p=0.007), and 46-60 years (p=0.024) but not in age group >60yrs (p=0.559). adjusting for menopausal status, densit...

introduction: breast cancer is the most common malignancy with more than one million new cases diagnosed annually all around the world. its growth is mostly regulated by steroid hormones such as estrogen and peptide growth factors in interaction with epidermal growth factor 1 and 2. methods and materials: in this study, 237 patients who had consulted the oncology clinic of tabriz university of ...

recent studies have shown that glucocorticoids may have modulatory effect on anxiety reactions. this effect may occur with opioid system interference. according to that, the purpose of this research is to assess the effect of dexamethasone as glucocorticoid agonist and its interaction with opioidergic system on the anxiety modulatory effect in plus maze model in mice. male white mice with mediu...

This review brings up to date material on the pulm'J:iary receptors with vagal afferent fibers. The­re a:·e essentially three typs of pulmonary receptors, 1) pulmonary stretch receptors, 2) irritant receptors, 3) type J pulmonary receptors. Their location, natu- 1 al stimulus, excitatory stimulus, reflex effects ancl their responses to chemical substances for three kind of recptas a,e discussed...

discussions in comparison to the control of wy14643, sandoz58-035, c9 and t11-cla, epa increased the pparα mrna levels (p = 0.024, p = 0.041, p = 0.043, and p = 0.004, respectively), even though, la had no significant effect on the pparα mrna expression (p = 0.489). materials and methods this experimental study investigated the effects of c9, t11-conjugated linoleic acid (c9, t11-cla). alpha li...