نتایج جستجو برای: acute toxicity

تعداد نتایج: 598490  

Journal: :بهره برداری و پرورش آبزیان 0
مجتبی علیشاهی دانشکده دامپزشکی دانشگاه شهید چمران اهواز اسماعیل عبدی دانشکده دامپزشکی دانشگاه شهید چمران اهواز

in this study the acute toxicity of organophosphorous pesticide in four native fishes of khouzestan province including: barbus sharpeyi, barbus grypus, barbus barbulus and barbus xanthopterus were investigated. the acute toxicity test was conducted following the organization for economic cooperation and development (oecd) under static-renewal test. each fish species exposed to serial dilution o...

Journal: :iranian journal of basic medical sciences 0
hasan badie bostan department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran soghra mehri department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran pharmaceutical research center, mashhad university of medical sciences, mashhad, iran neurocognitive research center, mashhad university of medical sciences, mashhad, iran hossein hosseinzadeh department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran pharmaceutical research center, mashhad university of medical sciences, mashhad, iran

saffron (crocus sativus l.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. the pharmacological properties of saffron and its main constituents, crocin and safranal have been evaluated using different in vivo and in vitro models. additionally, other lines of studies have found toxicological effects of saffron.  ho...

2015
Matthew Sean Peach Timothy N. Showalter Nitin Ohri

A small but meaningful percentage of men who are treated with external beam radiation therapy for prostate cancer will develop late gastrointestinal toxicity. While numerous strategies to prevent gastrointestinal injury have been studied, clinical trials concentrating on late toxicity have been difficult to carry out. Identification of subjects at high risk for late gastrointestinal injury coul...

Journal: :Radiation Oncology (London, England) 2007
Michael J Chen Eduardo Weltman Rodrigo M Hanriot Fábio P Luz Paulo J Cecílio José C da Cruz Frederico R Moreira Adriana S Santos Lidiane C Martins Wladmir Nadalin

BACKGROUND To report the toxicity after intensity modulated radiotherapy (IMRT) for patients with localized prostate cancer, as a sole treatment or after radical prostatectomy. METHODS Between August 2001 and December 2003, 132 patients with prostate cancer were treated with IMRT and 125 were evaluable to acute and late toxicity analysis, after a minimum follow-up time of one year. Clinical a...

Berberis vulgaris and berberine, its main component, traditionally have been used for treatment of various disorders. The pharmacological properties of them have been investigated using different in vivo and in vitro models. In spite of beneficial effects of B. vulgaris on different cell lines, there are documents have revealed negative impacts of it on animal and human. In this regards, the de...

2012
Ajaykumar B Patel Christopher L Hallemeier Ivy A Petersen Ashley W Jensen Thomas G Osborn Robert C Miller

BACKGROUND The purpose of this study was to evaluate acute and late toxicities of radiotherapy for patients with discoid lupus erythematosus (DLE). METHODS A retrospective review was performed of patients with DLE who received radiotherapy at our institution between 1980 and 2005. Patients with other connective tissue disorders were excluded. Control patients were matched 2:1 with the DLE tre...

ژورنال: سلامت و محیط زیست 2011
راستکاری, نوشین, زارع, محمدرضا, علی محمدی, محمود, موسوی, سیدنجات, ندافی, کاظم, یونسیان, مسعود,

Background and Objectives: This study was conducted to investigate the toxicity of Titanium Oxide (TiO2) and Zinc Oxide (ZnO) nanoparticles as two of most widely used nanoparticles. The result of this study can help to designing environmental standard and legislations for nanoparticles.Materials and Methods: Different concentrations of nano ZnO and TiO2 nanoparticles were added to nutrient Agar...

Journal: :Environmental toxicology and chemistry 2012
Gabriel S Weyman Hans Rufli Lennart Weltje Edward R Salinas Marc Hamitou

Aquatic toxicity tests with substances that are poorly soluble in water have been conducted using different methods, and estimates of toxicity have varied accordingly. The present study illustrates differences in toxicity values resulting from variation in test designs and solution preparation methods, and offers guidance on the best way to conduct these tests. Consequences for environmental ri...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2015
Barun Bhhatarai Daniel M Wilson Michael J Bartels Shubhra Chaudhuri Paul S Price Edward W Carney

There is great interest in assessing the in vivo toxicity of chemicals using nonanimal alternatives. However, acute mammalian toxicity is not adequately predicted by current in silico or in vitro approaches. Mechanisms of acute toxicity are likely conserved across invertebrate, aquatic, and mammalian species, suggesting that dose-response concordance would be high and in vitro mechanistic data ...

2016
Xiaonan Liu Jing Li Teresa Wu Steven E Schild Michael H Schild William Wong Sujay Vora Mirek Fatyga

AIM To model acute rectal toxicity in Intensity Modulated Radiation Therapy (IMRT) for prostate cancer using dosimetry and patient specific characteristics. METHODS A database of 79 prostate cancer patients treated with image guided IMRT was used to fit parameters of Lyman-Kutcher-Burman (LKB) and logistic regression Normal Tissue Complications Probability (NTCP) models to acute grade ≥ 2 rec...

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