Hepatocyte growth factor (HGF) is expressed as an angiogenic factor in adipose tissue. However, the molecular mechanism of Hgf expression remains largely unknown in the tissue. We addressed the issue by studying Hgf expression in adipocytes and macrophages. Hgf was expressed more in the stromal-vascular fraction than the adipocyte fraction. The expression was fivefold more in macrophages than t...

It has been noted that one of the most common types radiation injuries when a person is exposed to ionizing burns — severe local injuries. The aim study apply stromal and vascular fraction adipose tissue increase efficiency complex therapy for lesions. Materials methods study. In 2017-2019, 7 patients (all male; mean age (54.83±9.41) years) with lesions skin ulcerative-necrotic underlying tissu...

Cachexia affects about 80% of gastrointestinal cancer patients. This multifactorial syndrome resulting in involuntary and continuous weight loss is accompanied by systemic inflammation and immune cell infiltration in various tissues. Understanding the interactions among tumor, immune cells, and peripheral tissues could help attenuating systemic inflammation. Therefore, we investigated inflammat...

To meet the requirements for rapid tumor growth, a complex array of non-neoplastic cells are recruited to the tumor microenvironment. These cells facilitate tumor development by providing matrices, cytokines, growth factors, as well as vascular networks for nutrient and waste exchange, however their precise origins remain unclear. Through multicolored tissue transplant procedures; we have quant...

tem cell biology has made cell-based therapies promising. While the use of human embryonic stem cells is ethically controversial, adult stem cells attracts more and more attention from clinicians and scientists. Adult mesenchymal stem cells (MSC) are derived from various tissues, including bone marrow, subcutaneous adipose tissue, cruciate ligament, muscle, and synovium,1 which are potential do...