نتایج جستجو برای: advanced oxidation protein products

تعداد نتایج: 1800028  

Journal: :Journal of the American Society of Nephrology : JASN 2007
Hong Yan Li Fan Fan Hou Xun Zhang Ping Yan Chen Shang Xi Liu Jian Xun Feng Zhi Qiang Liu Yue Xin Shan Guo Bao Wang Zhan Mei Zhou Jian Wei Tian Di Xie

Accumulation of plasma advanced oxidation protein products (AOPP) has been found in patients with chronic kidney disease. However, the biologic consequences of AOPP consumption on progression of renal disease still are unclear. For testing of the hypothesis that AOPP accelerate progression of chronic kidney disease, Sprague-Dawley rats were subjected to five-sixths nephrectomy (5/6 Nx) or to sh...

Journal: :American journal of physiology. Renal physiology 2008
Yasunori Iwao Keisuke Nakajou Ryoji Nagai Kenichiro Kitamura Makoto Anraku Toru Maruyama Masaki Otagiri

Chronic accumulation of plasma advanced oxidation protein products (AOPPs) promotes renal fibrosis. However, the mechanism at the cellular level has not been clarified. In the present study, endocytic assay of human proximal tubular cells (HK-2 cells) demonstrated that AOPPs-human serum albumin (HSA) (in vitro preparations of chloramine- modified HSA) were significantly endocytosed in a dose-de...

Journal: :Molecular medicine reports 2015
Chiara Costa Silvia Gangemi Federica Giambò Venerando Rapisarda Daniela Caccamo Concettina Fenga

Previous evidence has demonstrated that chemical classes of pesticides, including organophosphates (OP), can induce oxidative stress in exposed workers. The resulting increase in free radicals causes damage to biological macromolecules, and promotes the formation of novel compounds, including advanced glycation end products (AGE) and advanced oxidation protein products (AOPP). The present study...

2016
La Salete Martins José C Oliveira José Ramón Vizcaíno Isabel Fonseca Carlos Gouveia Donzília Silva António C Henriques Irene L Noronha Anabela Rodrigues

Diabetes mellitus leads to increased Advanced Glycation End Products (AGE) production, which has been associated with secondary diabetic complications. Type 1 diabetic patients undergoing pancreas-kidney transplantation (SPKT) can restore normoglycemia and renal function, eventually decreasing AGE accumulation. We aimed to prospectively study AGE evolution after SPKT. Circulating AGE were asses...

2016
Pornpimon Nunthanawanich Weerachat Sompong Sukrit Sirikwanpong Kittana Mäkynen Sirichai Adisakwattana Winai Dahlan Sathaporn Ngamukote

Advanced glycation end products (AGEs) play an important factor for pathophysiology of diabetes and its complications. Moringa oleifera is one of the medicinal plants that have anti-hyperglycemic activity. However, anti-glycation property of Moringa oleifera leaf extract on the different types of reducing monosaccharides-induced protein glycation has not been investigated. Therefore, the aim of...

Background and purpose: Hyperglycemia contributes to type 2 diabetes and diabetes vascular complications by reduction of the activity of glyoxalase-I (GLO-I) and elevation of glycation, oxidative stress, and inflammatory markers. Linalool is reported to have beneficial effects on glucose metabolism in animal models of diabetes, so, this study aimed at investigating the effect of linalool on the...

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