1 AHP-Driven Knowledge Leakage Risk Assessment Model: A Construct-Apply-Control Cycle Approach; Haley Wing Chi Tsang, Knowledge Management and Innovation Research Centre, The Hong Kong Polytechnic University, Hong Kong Wing Bun Lee, Knowledge Management and Innovation Research Centre, The Hong Kong Polytechnic University, Hong Kong Eric Tsui, Knowledge Management and Innovation Research Centre,...

In this paper we argue that researchers in Intelligent Data Analysis (IDA) in Medicine and Pharmacology should consider textual databases as an additional source of knowledge. We describe three areas where medical knowledge extraction from textual databases can be fruitful: finding new applications for existing drugs, evolution of medical knowledge in time, and drug risk assessment. We evaluate...

Venous thromboembolism (VTE) is a frequent, multifactorial and potentially life-threatening disease [1–3]. When VTE occurs in the absence of any major risk factor (i.e. surgery, prolonged immobilisation or trauma of the lower limb), the risk of recurrent VTE is high (i.e. about 10% at 1 year and 30% at 5 years) after anticoagulation therapy is stopped, and current guidelines recommended indefin...

BACKGROUND Most treatment of patients at risk for stroke is provided in the ambulatory setting. Although many studies have addressed the proportion of eligible patients with atrial fibrillation (AF) receiving warfarin sodium, few have addressed the quality of their anticoagulation management. OBJECTIVE As a comprehensive assessment of quality, we analyzed the proportion of eligible patients r...

In patients with venous thromboembolism (VTE), assessment of the risk of fatal recurrent VTE and fatal bleeding during anticoagulation may help to guide intensity and duration of therapy. We aimed to provide estimates of the case-fatality rate (CFR) of recurrent VTE and major bleeding during anticoagulation in a 'real life' population, and to assess these outcomes according to the initial prese...

Table 1 Reported cases of well functioning mechanical valve without anticoagulation Reference Mean age n Type of Position Mean follow-up Treatment with Peak (years) valve (n) of valve period without anticoagulation gradient anticoagulation (months) across (years) valve thrombotic prophylaxis are from non-randomized case series without controls w2x. Uncomplicated functioning without anticoagulat...