BACKGROUND A drug delivery system that constitutively and effectively retains cardioprotective reagents in the targeted myocardium has long been sought to treat acute myocardial infarction. We hypothesized that a scaffold-free induced adipocyte cell-sheet (iACS), transplanted on the surface of the heart, might intramyocardially secrete multiple cardioprotective factors including adiponectin (AP...

Acquired Pendular Nystagmus (APN) may cause distressing visual symptoms in patients who are already suffering a severe general disease. Averbuch-Heller et al. conducted the first double-blind controlled study on treatment for APN. They showed that gabapentin substantially reduces pendular nystagmus and significantly increases visual acuity in the majority of patients. We present a patient with ...

It is well known that a quadratic function defined on a finite field of odd degree is almost bent (AB) if and only if it is almost perfect nonlinear (APN). For the even degree case there is no apparent relationship between the values in the Fourier spectrum of a function and the APN property. In this article we compute the Fourier spectrum of the quadranomial family of APN functions from [5]. W...

Adiponectin (APN) is an adipocyte protein with anti-diabetic properties, which has been recently revealed to have anti-inflammatory activity in organ ischemia- reperfusion injury (IRI). However, little is known about its function in bile duct IRI after liver transplantation. Therefore, we investigated whether APN affects early warm IRI in rat bile duct using a liver autologous transplantation m...

Two nitrile combinations, beta-aminopropionitrile (beta APN) with aminoacetonitrile (AAN) and betaAPN with beta APN (as a sham combination), were evaluated using the frog embryo mixture toxicity assay to determine their combined osteolathyritic effects and to compare the results with theoretical effects for two combined effects models. In separate tests each nitrile was tested with copper sulfa...

BACKGROUND Obesity is a risk factor for cardiovascular disease. Increasing evidence suggests that reduced levels of the adipocyte-derived plasma protein adiponectin are associated with an increased cardiovascular risk. Here, we examined the effects of adiponectin on lipopolysaccharide- (LPS-) induced acute cardiac injury in vivo. METHODS AND RESULTS A single dose of LPS (10 mg/kg) was intrape...

We find a one to one correspondence between quadratic APN functions without linear and constant terms and a special kind of matrices (We call such matrices as QAMs). Based on the nice mathematical structures of the QAMs, we have developed efficient algorithms to construct quadratic APN functions. On F27 , we have found more than 470 classes of new CCZ-inequivalent quadratic APN functions, which...

Establishing the CCZ-equivalence of a pair of APN functions is generally quite difficult. In some cases, when seeking to show that a putative new infinite family of APN functions is CCZ inequivalent to an already known family, we rely on computer calculation for small values of n. In this paper we present a method to prove the inequivalence of quadratic APN functions with the Gold functions. Ou...

For every positive integers n, m and every even positive integer δ, we derive inequalities satisfied by the Walsh transforms of all vectorial (n,m)-functions and prove that the case of equality characterizes differential δ-uniformity. This provides a generalization to all differentially δ-uniform functions of the characterization of APN (n, n)-functions due to Chabaud and Vaudenay, by means of ...