The authors of guidelines provide 100 recommendations describing many intensively discussed issues. Among them is hepatotoxicity of PTU and limitation of PTU treatment mainly to the first trimester of pregnancy. Methimazole becomes first line ATD for patients with new onset of Graves’ disease. Graves’ orbitopathy (GO) is classified according to its clinical activity and severity. Deterioration ...

tuberculosis in successive decades. Am J Epidemiol 2008;141:790. 41 Kermack WO, McKendrick AG, McKinley PL. Death-rates in Great Britain and Sweden. Some general regularities and their significance. Lancet 1934;31:683–703. 42 Susser M. Commentary: the longitudinal perspective and cohort analysis. Int J Epidemiol 2001;30:684–87. 43 Davey Smith G, Kuh D. Commentary: William Ogilvy Kermack and the...

The Shah-Kuh granitoid has intruded in the Triassic–Jurassic, pelitic and psammitic low-grade metamorphic rocks of the NE LutBlock, in Central Iran. Cordierite porphyroblasts are common in the southern pelitic sediments, but are rare in the northern psammiticrocks, in the contact aureole. Deformation fabrics in the contact aureole are well-preserved within the cordierite porphyroblasts. Therela...

the lut block (eastern iran) extends over 900 km in a north-south direction and is only 200 km wide in an east-west direction. it is confined by the nayband fault and shotori range on the west. the eastern edge is bordered by the sistan suture zone and nehbandan fault. the northern termination of lut block is the depression of kavir-e-namak and the great kavir fault. the makran arc, including t...

the shah-kuh granitoid has intruded in the triassic–jurassic, pelitic and psammitic low-grade metamorphic rocks of the ne lutblock, in central iran. cordierite porphyroblasts are common in the southern pelitic sediments, but are rare in the northern psammiticrocks, in the contact aureole. deformation fabrics in the contact aureole are well-preserved within the cordierite porphyroblasts. therela...

Allium formosum Sennikov & Lazkov sp. nov. is described as new to science and illustrated. This species is the second member of Allium sect. Spathulata F.O.Khass. & R.M.Fritsch, being different from Allium spathulatum F.O.Khass. & R.M.Fritsch in larger, broader, obtuse and more intensely purple-coloured tepals, and in a more robust habit. It is a local endemic of Babash-Ata Mt. Range situated e...

Angiotensin II (Ang II) has diverse effects on the glomerular tuft such as regulation of glomerular hemodynamics and stimulation of mesangial cell growth, and may be one pivotal factor in the progression of renal disease. In order to locally inactivate Ang II, we overexpressed aminopeptidase A (E.C. 3.4.11.7; ATA), a peptidase involved in the conversion of Ang II into angiotensin III, in a mous...

BACKGROUND The high incidence of persistent postconcussion symptoms in service members with combat-related mild traumatic brain injury has prompted research in the use of hyperbaric oxygen (HBO2) for management. OBJECTIVE The effects of HBO2 on persistent postconcussion symptoms in 60 military service members with at least 1 combat-related mild traumatic brain injury were examined in a single...

AIMS Inappropriate shocks have been an important issue post-implantable cardioverter-defibrillator (ICD) implantation. Moreover, inappropriate ICD shocks are associated with increased mortality. The objective of this study was to evaluate the feasibility of catheter ablation therapy for atrial tachyarrhythmias (ATa) responsible for inappropriate ICD shocks. METHODS AND RESULTS Among 108 conse...